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氨氯地平所致牙龈增生的激光辅助牙龈切除术:一例报告

Laser-Assisted Gingivectomy in Amlodipine-Induced Gingival Enlargement: A Case Report.

作者信息

Kaliyaperumal Rasica, Appusamy Kumar, Gokulraj Sabitha, Rajaram Mohan Karthik, Venkatraman Subhalakshmi

机构信息

Oral Medicine and Radiology, Vinayaka Mission's Sankarachariyar Dental College, Vinayaka Mission's Research Foundation (Deemed to be University), Salem, IND.

Oral Pathology and Microbiology, Vinayaka Mission's Sankarachariyar Dental College, Vinayaka Mission's Research Foundation (Deemed to be University), Salem, IND.

出版信息

Cureus. 2024 Dec 15;16(12):e75761. doi: 10.7759/cureus.75761. eCollection 2024 Dec.

DOI:10.7759/cureus.75761
PMID:39816282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11732961/
Abstract

Gingival enlargements are mostly plaque-induced. Other than plaque, a few genetic conditions also cause enlargements of the gingiva. In recent years, there has been a notable rise in drug-induced gingival overgrowth (DIGO) linked to the increased use of medications for various systemic conditions. Commonly implicated drug classes include antihypertensives, anticonvulsants, immunosuppressants, and calcium channel blockers. These medications can lead to gingival overgrowth, which adversely affects oral function, esthetics, and hygiene. In this paper, we report the case of a 47-year-old male patient with hypertension who experienced amlodipine-induced gingival enlargement. In this case report, laser was also incorporated into the treatment plan for the reduction of gingival growth.

摘要

牙龈增生大多由菌斑引起。除菌斑外,一些遗传疾病也会导致牙龈增生。近年来,由于用于各种全身性疾病的药物使用增加,药物性牙龈增生(DIGO)显著增多。常见的相关药物类别包括抗高血压药、抗惊厥药、免疫抑制剂和钙通道阻滞剂。这些药物会导致牙龈增生,对口腔功能、美观和卫生产生不利影响。在本文中,我们报告了一名47岁男性高血压患者出现氨氯地平引起的牙龈增生的病例。在本病例报告中,激光也被纳入治疗方案以减少牙龈增生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d3b/11732961/9cc1b27e3a64/cureus-0016-00000075761-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d3b/11732961/32ccaa3de06a/cureus-0016-00000075761-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d3b/11732961/b68713c65e1e/cureus-0016-00000075761-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d3b/11732961/0170fb27a366/cureus-0016-00000075761-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d3b/11732961/9cc1b27e3a64/cureus-0016-00000075761-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d3b/11732961/32ccaa3de06a/cureus-0016-00000075761-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d3b/11732961/b68713c65e1e/cureus-0016-00000075761-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d3b/11732961/0170fb27a366/cureus-0016-00000075761-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d3b/11732961/9cc1b27e3a64/cureus-0016-00000075761-i04.jpg

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本文引用的文献

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Novel Insights into Amlodipine-Induced Gingival Enlargement: A Clinical and Molecular Perspective.氨氯地平所致牙龈增生的新见解:临床与分子视角
Pharmaceuticals (Basel). 2024 Aug 16;17(8):1075. doi: 10.3390/ph17081075.
2
The Management of Drug-Induced Gingival Enlargement in a Patient With Preexisting Periodontitis.一名已有牙周炎患者药物性牙龈增生的管理
Cureus. 2024 Jan 12;16(1):e52190. doi: 10.7759/cureus.52190. eCollection 2024 Jan.
3
Treatment of Gingival Growth Due to Amlodipine Use With a 445-nm Diode Laser: A Case Report.
使用445纳米二极管激光治疗氨氯地平引起的牙龈增生:病例报告
Cureus. 2022 Dec 16;14(12):e32592. doi: 10.7759/cureus.32592. eCollection 2022 Dec.
4
Bibliometric analysis of research trends and characteristics of drug-induced gingival overgrowth.药物性牙龈过度增生的研究趋势和特征的文献计量分析。
Front Public Health. 2022 Sep 6;10:979861. doi: 10.3389/fpubh.2022.979861. eCollection 2022.
5
Calcium Channel Blockers Induced Gingival Overgrowth: A Comprehensive Review from a Dental Perspective.钙通道阻滞剂所致牙龈增生:从牙科角度的全面综述
J Int Soc Prev Community Dent. 2022 Jun 29;12(3):309-322. doi: 10.4103/jispcd.JISPCD_57_22. eCollection 2022 May-Jun.
6
Drug-Induced Gum Overgrowth With Low-Dose Amlodipine: A Case Report.低剂量氨氯地平所致药物性牙龈增生:一例报告
Cureus. 2022 May 22;14(5):e25220. doi: 10.7759/cureus.25220. eCollection 2022 May.
7
Amlodipine induced gingival enlargement.氨氯地平引起牙龈增生。
BMJ Case Rep. 2021 Aug 3;14(8):e245098. doi: 10.1136/bcr-2021-245098.
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Is dental plaque the only etiological factor in Amlodipine induced gingival overgrowth? A systematic review of evidence.牙菌斑是氨氯地平所致牙龈增生的唯一病因吗?证据的系统评价
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