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胃食管反流病管理的非药物治疗方法

Non-Pharmacological approach for the management of gastroesophageal reflux disease.

作者信息

Randhawa Mohammad Akram, Khan Sadia Azam, Naseer Aqsa, Baqai Muhammad Tariq

机构信息

Mohammad Akram Randhawa, MBBS, PhD. Professor, Department of Pharmacology and Therapeutics, Rawalpindi Medical University, Rawalpindi, Pakistan.

Sadia Azam Khan, MBBS, MRCGP. Assistant Professor, Head of Department of Family Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan.

出版信息

Pak J Med Sci. 2024 Jan-Feb;40(3Part-II):549-551. doi: 10.12669/pjms.40.3.7291.

Abstract

Treatment of Gastro-Esophageal Reflux Disease (GERD) is becoming a challenge. Proton pump inhibitors (PPIs) are commonly prescribed but have many risks, particularly in long-term use. In an earlier pilot study, we have reported benefits of short-term practice of a new life-style, two meals a day with only liquids in between, for management of GERD. Present case report demonstrates benefits of long-term practice of this dietary regimen. A 61 year old patient complaining of night refluxes was diagnosed to have severe GERD with ulcerations at gastroesophageal junction and was advised to take two meals a day with only water, fruit juice, tea, or milk in intervening period. His reflux symptoms improved within fortnight and he remained well for long-time. Endoscopy done after seven years revealed competent and clear gastroesophageal junction. It is concluded that suggested life-style, "Akram's life-style", for GERD is a useful alternate to risky medical and surgical interventions.

摘要

胃食管反流病(GERD)的治疗正成为一项挑战。质子泵抑制剂(PPIs)是常用药物,但存在诸多风险,尤其是长期使用时。在一项早期的试点研究中,我们报告了一种新的生活方式短期实践的益处,即一天两餐,中间仅摄入液体,用于GERD的管理。本病例报告展示了这种饮食方案长期实践的益处。一名61岁抱怨夜间反流的患者被诊断为患有严重的GERD,胃食管交界处有溃疡,建议其一天两餐,中间仅喝水、果汁、茶或牛奶。他的反流症状在两周内得到改善,并且长时间保持良好状态。七年后进行的内镜检查显示胃食管交界处功能正常且清晰。结论是,所建议的GERD生活方式“阿克拉姆生活方式”是有风险的药物和手术干预的有用替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584a/10862460/03074069564b/PJMS-40-549-g001.jpg

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