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中药源细胞外囊泡样颗粒研究与应用的共识声明(2023年版)

Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles (2023 edition).

作者信息

Zhao Qing, Wang Tong, Wang Hongbin, Cao Peng, Jiang Chengyu, Qiao Hongzhi, Peng Lihua, Lin Xingdong, Jiang Yunyao, Jin Honglei, Zhang Huantian, Wang Shengpeng, Wang Yang, Wang Ying, Chen Xi, Fan Junbing, Li Bo, Li Geng, Liu Bifeng, Li Zhiyang, Qi Suhua, Zhang Mingzhen, Zheng Jianjian, Zhou Jiuyao, Zheng Lei, Zhao Kewei

机构信息

Guangdong Engineering Research Center of Chinese Herbal Vesicles, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510378, China.

Guangzhou Key Laboratory of Chinese Medicine Research on Prevention and Treatment of Osteoporosis, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510378, China.

出版信息

Chin Herb Med. 2023 Dec 14;16(1):3-12. doi: 10.1016/j.chmed.2023.11.002. eCollection 2024 Jan.

Abstract

To promote the development of extracellular vesicles of herbal medicine especially the establishment of standardization, led by the National Expert Committee on Research and Application of Chinese Herbal Vesicles, research experts in the field of herbal medicine and extracellular vesicles were invited nationwide with the support of the Expert Committee on Research and Application of Chinese Herbal Vesicles, Professional Committee on Extracellular Vesicle Research and Application, Chinese Society of Research Hospitals and the Guangdong Engineering Research Center of Chinese Herbal Vesicles. Based on the collation of relevant literature, we have adopted the Delphi method, the consensus meeting method combined with the nominal group method to form a discussion draft of "Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles (2023)". The first draft was discussed in online and offline meetings on October 12, 14, November 2, 2022 and April and May 2023 on the current status of research, nomenclature, isolation methods, quality standards and research applications of extracellular vesicles of Chinese herbal medicines, and 13 consensus opinions were finally formed. At the Third Academic Conference on Research and Application of Chinese Herbal Vesicles, held on May 26, 2023, Kewei Zhao, convenor of the consensus, presented and read the consensus to the experts of the Expert Committee on Research and Application of Chinese Herbal Vesicles. The consensus highlights the characteristics and advantages of Chinese medicine, inherits the essence, and keeps the righteousness and innovation, aiming to provide a reference for colleagues engaged in research and application of Chinese herbal vesicles at home and abroad, decode the mystery behind Chinese herbal vesicles together, establish a safe, effective and controllable accurate Chinese herbal vesicle prevention and treatment system, and build a bridge for Chinese medicine to the world.

摘要

为推动中草药细胞外囊泡的发展,尤其是标准化的建立,在中草药囊泡研究与应用国家专家委员会的牵头下,在中草药囊泡研究与应用专家委员会、细胞外囊泡研究与应用专业委员会、中国研究型医院学会以及广东省中草药囊泡工程技术研究中心的支持下,邀请了全国中草药和细胞外囊泡领域的研究专家。在整理相关文献的基础上,我们采用德尔菲法、共识会议法并结合名义群体法,形成了《中草药来源的细胞外囊泡样颗粒研究与应用共识声明(2023年)》讨论稿。初稿于2022年10月12日、14日、11月2日以及2023年4月和5月通过线上和线下会议,就中草药细胞外囊泡的研究现状、命名、分离方法、质量标准及研究应用等进行了讨论,最终形成13条共识意见。在2023年5月26日举行的第三届中草药囊泡研究与应用学术会议上,共识召集人赵柯炜向中草药囊泡研究与应用专家委员会的专家们展示并宣读了该共识。该共识突出中医药特色优势,传承精华,守正创新,旨在为国内外从事中草药囊泡研究与应用的同仁提供参考,共同解码中草药囊泡背后的奥秘,建立安全、有效、可控的精准中草药囊泡防治体系,为中医药走向世界搭建桥梁。

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