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Endogenous prostaglandins and stimulated gastric secretion in the cat: the effect of various secretory inhibitors.内源性前列腺素与猫的胃酸分泌：各种分泌抑制剂的作用
J Physiol. 1979 Jun;291:1-9. doi: 10.1113/jphysiol.1979.sp012794.
2
Endogenous prostaglandins and gastric secretion in the cat.猫体内的内源性前列腺素与胃液分泌
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Prostaglandins alter the relationship between gastric hydrogen ion concentration and flow: evidence for stimulation of non-parietal secretion in the cat.前列腺素改变胃氢离子浓度与流量之间的关系：猫非壁细胞分泌受刺激的证据。
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Exogenous prostaglandins and gastric secretion in the cat.猫体内的外源性前列腺素与胃液分泌
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Stimulated gastric prostaglandin output, and the effect of inhibition of prostaglandin synthetase, in the conscious cat.清醒猫体内刺激后的胃前列腺素分泌以及前列腺素合成酶抑制作用的效果
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Effect of cimetidine on histamine- and pentagastrin-stimulated gastric secretion in healthy subjects.西咪替丁对健康受试者组胺和五肽胃泌素刺激的胃酸分泌的影响。
Scand J Gastroenterol. 1979;14(3):367-72. doi: 10.3109/00365527909179898.
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Relationship between hydrogen ion concentration and flow of gastric juice during inhibition of gastric secretion in the cat.猫胃液分泌受抑制期间氢离子浓度与胃液分泌量之间的关系
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The effects of somatostatin and metiamide on tachyphylaxis of pentagastrin stimulated gastric acid and pepsin secretion in the conscious cat.生长抑素和甲硫咪特对清醒猫中五肽胃泌素刺激的胃酸和胃蛋白酶分泌快速耐受的影响。
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[Inhibition of stimulated gastric secretion with simultaneous administration of cimetidine and somatostatin].
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引用本文的文献

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Changes in cardiac output and its distribution after non-haemorrhagic injury in the rat.大鼠非出血性损伤后心输出量及其分布的变化。
Br J Exp Pathol. 1980 Aug;61(4):421-8.
2
Stimulated gastric prostaglandin output, and the effect of inhibition of prostaglandin synthetase, in the conscious cat.清醒猫体内刺激后的胃前列腺素分泌以及前列腺素合成酶抑制作用的效果
J Physiol. 1981 Aug;317:21-8. doi: 10.1113/jphysiol.1981.sp013811.

本文引用的文献

1
Effect of nerve stimulation on prostaglandin formation and release from the rat stomach.神经刺激对大鼠胃中前列腺素形成和释放的影响。
Am J Physiol. 1967 Oct;213(4):1056-64. doi: 10.1152/ajplegacy.1967.213.4.1056.
2
Prostaglandin inhibition of gastric secretion.前列腺素对胃液分泌的抑制作用。
J Physiol. 1968 Mar;195(2):34P-36P.
3
Radioimmunoassay for prostaglandins.前列腺素的放射免疫测定法。
Science. 1971 Feb 5;171(3970):494-6. doi: 10.1126/science.171.3970.494.
4
Biosynthesis of prostaglandins E2 and F2-alpha from tritium-labelled arachidonic acid by rat stomach homogenates.大鼠胃匀浆从氚标记的花生四烯酸生物合成前列腺素E2和F2-α 。
Biochim Biophys Acta. 1970 Dec 15;218(3):539-42. doi: 10.1016/0005-2760(70)90017-2.
5
The separate determination of human pepsin and gastricsin.人胃蛋白酶和胃凝乳蛋白酶的单独测定
Proc Soc Exp Biol Med. 1966 Jul;122(3):700-4. doi: 10.3181/00379727-122-31231.
6
Prostaglandin synthetase activity in the rat stomach fundus. Activation by L-norepinephrine and related compounds.大鼠胃底中的前列腺素合成酶活性。L-去甲肾上腺素及相关化合物的激活作用。
Biochim Biophys Acta. 1972 Sep 7;280(1):161-71. doi: 10.1016/0005-2760(72)90221-4.
7
Inhibition of human gastric secretion by prostaglandin.前列腺素对人胃液分泌的抑制作用。
Br J Surg. 1973 Oct;60(10):828-31. doi: 10.1002/bjs.1800601018.
8
Radioimmunoassay measurement of prostaglandins E, A, and F in human plasma.人血浆中前列腺素E、A和F的放射免疫分析测定
J Clin Invest. 1973 Feb;52(2):398-405. doi: 10.1172/JCI107196.
9
Inhibition by prostaglandin E 1 of gastric secretion in the dog.前列腺素E1对犬胃液分泌的抑制作用。
J Physiol. 1971 Oct;218(2):369-83. doi: 10.1113/jphysiol.1971.sp009623.
10
Hypotheses on physiological roles of prostaglandins.关于前列腺素生理作用的假说。
Physiol Rev. 1969 Jan;49(1):122-61. doi: 10.1152/physrev.1969.49.1.122.

内源性前列腺素与猫的胃酸分泌：各种分泌抑制剂的作用

Endogenous prostaglandins and stimulated gastric secretion in the cat: the effect of various secretory inhibitors.

作者信息

Baker R, Jaffe B M, Reed J D, Shaw B, Venables C W

出版信息

J Physiol. 1979 Jun;291:1-9. doi: 10.1113/jphysiol.1979.sp012794.

DOI:10.1113/jphysiol.1979.sp012794
PMID:383948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1280882/
Abstract
  1. The effects of cimetidine, somatostatin and atropine upon the outputs of acid, pepsin, prostaglandins (PG) E and F in gastric juice secreted in response to i.v. infusions of pentagastrin and histamine (H) have been studied in the conscious gastric fistula cat. 2. At constant rate infusions secretion of PGE occurs and follows a similar pattern to that of gastric acid. However the ratio of H:PGE varies considerably and to an extent inexplicable in terms of assay variation. 3. Inhibition of acid output is matched by inhibition of the output of PGE, but changes in concentration of PGE suggest this is a volume related phenomenon. 4. It is concluded that gastric juice PGE is most unlikely to have a regulatory effect upon acid secretion.
摘要
  1. 研究了西咪替丁、生长抑素和阿托品对清醒胃瘘猫静脉输注五肽胃泌素和组胺（H）后胃液中酸、胃蛋白酶、前列腺素（PG）E和F分泌量的影响。2. 以恒定速率输注时，PGE分泌出现，且其模式与胃酸分泌相似。然而，H:PGE的比值变化很大，且在某种程度上无法用检测变化来解释。3. 酸分泌的抑制与PGE分泌的抑制相匹配，但PGE浓度的变化表明这是一个与体积相关的现象。4. 得出的结论是，胃液中的PGE极不可能对胃酸分泌产生调节作用。