猫体内的外源性前列腺素与胃液分泌
Exogenous prostaglandins and gastric secretion in the cat.
作者信息
Baker R, Jaffe B M, Reed J D, Shaw B, Venables C W
出版信息
J Physiol. 1978 May;278:441-50. doi: 10.1113/jphysiol.1978.sp012315.
Abstract
- In the conscious gastric fistula cate PGE2 was shown to produce dose-related inhibition of gastric acid and pepsin secreted in response to pentagastrin, histamine and insulin. 2. PGF2alpha had little effect on pentagastrin-stimulated gastric acid and pepsin secretion. 3PGF2 delayed the tachyphylaxis of gastric acid stimulated by pentagastrin and histamine, but not that stimulated by insulin. 4. Although not delaying tachyphylaxis of insulin stimulated acid, PGE2 delayed tachyphylaxis of insulin stimulated pepsin.
摘要
- 在清醒胃瘘猫中，已表明前列腺素E2（PGE2）能对由五肽胃泌素、组胺和胰岛素刺激分泌的胃酸和胃蛋白酶产生剂量相关的抑制作用。2. 前列腺素F2α（PGF2α）对五肽胃泌素刺激的胃酸和胃蛋白酶分泌几乎没有影响。3. PGF2能延缓由五肽胃泌素和组胺刺激的胃酸快速耐受现象，但不能延缓由胰岛素刺激的胃酸快速耐受现象。4. 虽然PGE2不能延缓胰岛素刺激胃酸的快速耐受现象，但它能延缓胰岛素刺激胃蛋白酶的快速耐受现象。
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Exogenous prostaglandins and gastric secretion in the cat.猫体内的外源性前列腺素与胃液分泌
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2
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引用本文的文献
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Stimulated gastric prostaglandin output, and the effect of inhibition of prostaglandin synthetase, in the conscious cat.清醒猫体内刺激后的胃前列腺素分泌以及前列腺素合成酶抑制作用的效果
J Physiol. 1981 Aug;317:21-8. doi: 10.1113/jphysiol.1981.sp013811.
2
Are prostaglandins involved in somatostatin mediated inhibition of gastric secretion in the cat?前列腺素是否参与了生长抑素介导的猫胃分泌抑制过程？
Agents Actions. 1986 Apr;18(1-2):205-9. doi: 10.1007/BF01988022.
3
Endogenous prostaglandins in peptic ulcer disease.消化性溃疡疾病中的内源性前列腺素
Gut. 1979 May;20(5):394-9. doi: 10.1136/gut.20.5.394.
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Prostaglandins and serotonin: nonpeptide diarrheogenic hormones.前列腺素和血清素：非肽类致泻激素。
World J Surg. 1979 Sep 20;3(5):565-78. doi: 10.1007/BF01654761.
5
Endogenous prostaglandins and gastric secretion in the cat.猫体内的内源性前列腺素与胃液分泌
J Physiol. 1978 May;278:451-60. doi: 10.1113/jphysiol.1978.sp012316.
本文引用的文献
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The separate determination of human pepsin and gastricsin.人胃蛋白酶和胃凝乳蛋白酶的单独测定
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Effect of metiamide, a histamine H2-receptor antagonist, on gastric response to histamine, pentagastrin, insulin, and peptone meal in man.组胺H2受体拮抗剂甲硫米特对人体胃对组胺、五肽胃泌素、胰岛素和蛋白胨餐反应的影响。
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Comparison of prostaglandin E1 and norepinephrine on the gastric mucosal circulation.前列腺素E1与去甲肾上腺素对胃黏膜循环的比较
Proc Soc Exp Biol Med. 1970 Feb;133(2):516-9. doi: 10.3181/00379727-133-34509.
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Release of prostaglandin E-1 from the rat stomach.前列腺素E-1从大鼠胃中的释放。
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Hypotheses on physiological roles of prostaglandins.关于前列腺素生理作用的假说。
Physiol Rev. 1969 Jan;49(1):122-61. doi: 10.1152/physrev.1969.49.1.122.
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Occurrence of prostaglandin E2 in the human stomach, and a study of its effects on human isolated gastric muscle.前列腺素E2在人胃中的存在及其对人离体胃肌影响的研究。
Br J Pharmacol Chemother. 1968 Feb;32(2):339-49.
10
Effects of isopropylnoradrenaline on tachyphylaxis of gastrin stimulated gastric acid secretion and mucosal blood flow in the anaesthetized cat.异丙肾上腺素对麻醉猫胃泌素刺激的胃酸分泌速发性耐受和黏膜血流的影响。
J Physiol. 1976 Jan;254(1):153-68. doi: 10.1113/jphysiol.1976.sp011226.
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