文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

纳米颗粒介导的双链 RNA 递送来进行精准的害虫防治:全面综述。

Nanoparticle-mediated dsRNA delivery for precision insect pest control: a comprehensive review.

机构信息

Division of Molecular Entomology, Department of Zoology, School of Life Sciences, Periyar University, Salem, 636011, India.

Division of Genomic Resources, ICAR-National Bureau of Agricultural Insect Resources, H.A. Farm Post, Hebbal, P.B. No. 2491, Bangalore, 560024, India.

出版信息

Mol Biol Rep. 2024 Feb 24;51(1):355. doi: 10.1007/s11033-023-09187-6.


DOI:10.1007/s11033-023-09187-6
PMID:38400844
Abstract

Nanoparticle-based delivery systems have emerged as powerful tools in the field of pest management, offering precise and effective means of delivering double-stranded RNA (dsRNA), a potent agent for pest control through RNA interference (RNAi). This comprehensive review aims to evaluate and compare various types of nanoparticles for their suitability in dsRNA delivery for pest management applications. The review begins by examining the unique properties and advantages of different nanoparticle materials, including clay, chitosan, liposomes, carbon, gold and silica. Each material's ability to protect dsRNA from degradation and its potential for targeted delivery to pests are assessed. Furthermore, this review delves into the surface modification strategies employed to enhance dsRNA delivery efficiency. Functionalization with oligonucleotides, lipids, polymers, proteins and peptides is discussed in detail, highlighting their role in improving stability, cellular uptake, and specificity of dsRNA delivery.This review also provides valuable guidance on choosing the most suitable nanoparticle-based system for delivering dsRNA effectively and sustainably in pest management. Moreover, it identifies existing knowledge gaps and proposes potential research directions aimed at enhancing pest control strategies through the utilization of nanoparticles and dsRNA.

摘要

纳米粒子基递药系统已成为害虫管理领域的有力工具,为通过 RNA 干扰(RNAi)来控制害虫提供了精确有效的双链 RNA(dsRNA)传递手段。本综述旨在评估和比较各种类型的纳米粒子在 dsRNA 传递方面用于害虫管理应用的适用性。本综述首先考察了不同纳米粒子材料(包括粘土、壳聚糖、脂质体、碳、金和二氧化硅)的独特性质和优势。评估了每种材料保护 dsRNA 免受降解的能力及其将 dsRNA 靶向递送至害虫的潜力。此外,本综述深入探讨了用于提高 dsRNA 传递效率的表面修饰策略。详细讨论了与寡核苷酸、脂质、聚合物、蛋白质和肽的功能化,强调了它们在提高 dsRNA 传递稳定性、细胞摄取和特异性方面的作用。本综述还就如何选择最适合的基于纳米粒子的系统以有效和可持续地在害虫管理中传递 dsRNA 提供了有价值的指导。此外,它还确定了现有知识空白,并提出了通过利用纳米粒子和 dsRNA 增强害虫控制策略的潜在研究方向。

相似文献

[1]
Nanoparticle-mediated dsRNA delivery for precision insect pest control: a comprehensive review.

Mol Biol Rep. 2024-2-24

[2]
Strategies for enhancing the efficiency of RNA interference in insects.

Pest Manag Sci. 2021-6

[3]
Nanoparticle-mediated double-stranded RNA delivery system: A promising approach for sustainable pest management.

Insect Sci. 2021-2

[4]
[Strategies for exogenous RNA delivery in RNAi-mediated pest management].

Sheng Wu Gong Cheng Xue Bao. 2023-2-25

[5]
Practical Use of RNA Interference: Oral Delivery of Double-stranded RNA in Liposome Carriers for Cockroaches.

J Vis Exp. 2018-5-1

[6]
Advances in exogenous RNA delivery techniques for RNAi-mediated pest control.

Mol Biol Rep. 2020-8

[7]
RNA interference in insects: the link between antiviral defense and pest control.

Insect Sci. 2024-2

[8]
Functional characterization of developmentally critical genes in the white-backed planthopper: Efficacy of nanoparticle-based dsRNA sprays for pest control.

Pest Manag Sci. 2023-3

[9]
Examination of the Suitability of Attractive Target Genes for RNAi-Based Pest Control.

Methods Mol Biol. 2022

[10]
Application of Nanoparticle-Mediated RNAi for Efficient Gene Silencing and Pest Control on Soybean Aphids.

Methods Mol Biol. 2022

引用本文的文献

[1]
Bt in the Spotlight: Defending Its Relevance in an RNAi-Driven Future.

Insects. 2025-8-14

[2]
Mechanisms and Genetic Drivers of Resistance of Insect Pests to Insecticides and Approaches to Its Control.

Toxics. 2025-8-16

[3]
Toxicological and Functional Assessment of Minicell-Encapsulated dsRNA on Biocontrol Agents in Agriculture.

ACS Environ Au. 2025-6-17

[4]
Trans-Kingdom sRNA Silencing in for Crop Fungal Disease Management.

Pathogens. 2025-4-21

[5]
Rapid Genotyping of Mutation in Sheep Using CRISPR-Cas12a Integrated with DNA Nanotree Biosensing Platform.

Biomolecules. 2025-2-20

[6]
Effects of Double-Stranded RNA Degrading Nucleases on RNAi Efficiency in Beet Moth (Lepidoptera: Noctuidae).

Insects. 2025-2-19

[7]
Development and Evaluation of Docetaxel-Loaded Nanostructured Lipid Carriers for Skin Cancer Therapy.

Pharmaceutics. 2024-7-19

[8]
Recent advances in understanding of the mechanisms of RNA interference in insects.

Insect Mol Biol. 2024-7-3

[9]
Challenges of Robust RNAi-Mediated Gene Silencing in Mosquitoes.

Int J Mol Sci. 2024-5-10

本文引用的文献

[1]
Conjugation of microbial-derived gold nanoparticles to different types of nucleic acids: evaluation of transfection efficiency.

Sci Rep. 2023-9-6

[2]
Electrochemical Synthesis of Carbon Quantum Dots.

ChemElectroChem. 2023-2-1

[3]
Nanoparticle-Shielded dsRNA Delivery for Enhancing RNAi Efficiency in Cotton Spotted Bollworm (Lepidoptera: Nolidae).

Int J Mol Sci. 2023-5-23

[4]
GL67 lipid-based liposomal formulation for efficient siRNA delivery into human lung cancer cells.

Saudi Pharm J. 2023-7

[5]
Recent Advances in DNA Origami-Engineered Nanomaterials and Applications.

Chem Rev. 2023-4-12

[6]
Recent Advances in Nanoparticle-Mediated Co-Delivery System: A Promising Strategy in Medical and Agricultural Field.

Int J Mol Sci. 2023-3-7

[7]
Simultaneous silencing of juvenile hormone metabolism genes through RNAi interrupts metamorphosis in the cotton boll weevil.

Front Mol Biosci. 2023-3-6

[8]
Impact of dispersion media and carrier type on spray-dried proliposome powder formulations loaded with beclomethasone dipropionate for their pulmonary drug delivery via a next generation impactor.

PLoS One. 2023

[9]
Gene silencing for invasive paper wasp management: Synthesized dsRNA can modify gene expression but did not affect mortality.

PLoS One. 2023

[10]
Chitosan nanocarriers mediated dsRNA delivery in gene silencing for Helicoverpa armigera biocontrol.

Pestic Biochem Physiol. 2023-1

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索