Ezaki M, Iwami M, Yamashita M, Hashimoto S, Komori T, Umehara K, Mine Y, Kohsaka M, Aoki H, Imanaka H
J Antibiot (Tokyo). 1985 Nov;38(11):1453-61. doi: 10.7164/antibiotics.38.1453.
Biphenomycin A, C23H28N4O8, and biphenomycin B, C23H28N4O7, were isolated from the cultured broth of Streptomyces griseorubiginosus No. 43708. The antibiotics are active in vitro and in vivo against bacteria, and are especially potent against Gram-positive bacteria. The acute toxicity of biphenomycin A is very low in mice.
双苯霉素A(C23H28N4O8)和双苯霉素B(C23H28N4O7)是从灰色红菌素链霉菌43708号菌株的培养液中分离得到的。这两种抗生素在体外和体内均对细菌有活性,尤其对革兰氏阳性菌有强效。双苯霉素A对小鼠的急性毒性非常低。