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绿色空间、压力与健康:表观遗传学在其中起到了怎样的作用?

Greenspace, stress, and health: how is epigenetics involved?

作者信息

Nwanaji-Enwerem Ugoji, McGeary John E, Grigsby-Toussaint Diana S

机构信息

Department of Behavioral and Social Sciences, Brown University School of Public Health, Warren Alpert Medical School of Brown University, Providence, RI, United States.

Providence VA Medical Center, Providence, RI, United States.

出版信息

Front Public Health. 2024 Feb 16;12:1333737. doi: 10.3389/fpubh.2024.1333737. eCollection 2024.

DOI:10.3389/fpubh.2024.1333737
PMID:38435282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10906089/
Abstract

Most expositions of the association between green space and overall health and well-being focus on psychosocial mechanisms. However, discussions of the biological underpinnings of the exposure to green space and health implications are limited. In this paper, we highlight the role epigenetics plays in the manifestation or suppression of stress, in addition to some of the proposed epigenetic mechanisms through which green space mitigates stress. The Health: Epigenetics, Greenspace and Stress (HEGS) model is introduced to explicate this association, and suggestions for research to build the evidence base in this area are discussed.

摘要

大多数关于绿地与整体健康及幸福之间关联的阐述都聚焦于社会心理机制。然而,关于接触绿地的生物学基础及其对健康影响的讨论却很有限。在本文中,我们强调了表观遗传学在压力的显现或抑制中所起的作用,此外还介绍了一些绿地减轻压力的表观遗传机制。我们引入了健康:表观遗传学、绿地与压力(HEGS)模型来阐释这种关联,并讨论了在该领域开展研究以建立证据基础的相关建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48b1/10906089/3f4f34d04a64/fpubh-12-1333737-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48b1/10906089/3f4f34d04a64/fpubh-12-1333737-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48b1/10906089/3f4f34d04a64/fpubh-12-1333737-g001.jpg

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本文引用的文献

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The association between prenatal greenspace exposure and Autism spectrum disorder, and the potentially mediating role of air pollution reduction: A population-based birth cohort study.产前绿地暴露与自闭症谱系障碍的关联,以及空气污染减排的潜在中介作用:基于人群的出生队列研究。
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Prenatal Exposure to Ambient Air Pollution and Epigenetic Aging at Birth in Newborns.新生儿出生前暴露于环境空气污染与表观遗传衰老
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Innovation (Camb). 2021 Sep 24;2(4):100164. doi: 10.1016/j.xinn.2021.100164. eCollection 2021 Nov 28.
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