Zhong Shihao, Xin Zhengyuan, Hou Yaozhen, Li Yang, Huang Hen-Wei, Sun Tao, Shi Qing, Wang Huaping
Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing 100081, China.
Peking University First Hospital, Beijing 100034, China.
Cyborg Bionic Syst. 2024 Jan 8;6:0077. doi: 10.34133/cbsystems.0077. eCollection 2024.
Flexible miniature robots are expected to enter difficult-to-reach areas in vivo to carry out targeted operations, attracting widespread attention. However, it is challenging for the existing soft miniature robots to substantially alter their stable shape once the structure is designed. This limitation leads to a fixed motion mode, which subsequently restricts their operating environment. In this study, we designed a biocompatible flexible miniature robot with a variable stable form that is capable of adapting to complex terrain environments through multiple movement modes. Inspired by the reversible stretching reaction of alginate saline gel stimulated by changes in environmental ion concentration, we manufactured a morphologically changeable super-soft hydrogel miniature robot body. According to the stretch and contraction shapes of the flexible hydrogel miniature robot, we designed magnetic fields for swing and rolling motion modes to realize multi-shape movement. The experimental results demonstrate that the deflection angle of the designed flexible miniature robot is reversible and can reach a maximum of 180°. The flexible miniature robot can complete forward swinging in the bar stretch state and tumbling motion in the spherical state. We anticipate that flexible hydrogel miniature robots with multiple morphologies and multimodal motion have great potential for biomedical applications in complex, unstructured, and enclosed living environments.
柔性微型机器人有望进入体内难以到达的区域进行靶向操作,这引起了广泛关注。然而,对于现有的软微型机器人来说,一旦结构设计完成,要大幅改变其稳定形状具有挑战性。这种限制导致了固定的运动模式,进而限制了它们的操作环境。在本研究中,我们设计了一种具有可变稳定形态的生物相容性柔性微型机器人,它能够通过多种运动模式适应复杂的地形环境。受环境离子浓度变化刺激的海藻酸盐盐水凝胶可逆拉伸反应的启发,我们制造了一种形态可变的超软水凝胶微型机器人主体。根据柔性水凝胶微型机器人的伸缩形状,我们设计了用于摆动和滚动运动模式的磁场,以实现多形状运动。实验结果表明,所设计的柔性微型机器人的偏转角是可逆的,最大可达180°。柔性微型机器人可以在杆状拉伸状态下完成向前摆动,在球状状态下完成翻滚运动。我们预计,具有多种形态和多模态运动的柔性水凝胶微型机器人在复杂、非结构化和封闭的生活环境中的生物医学应用具有巨大潜力。