Michigan State University College of Human Medicine, Grand Rapids, MI, USA.
Department of Cutaneous Surgery and Dermatology, University of Miami, Miami, FL, USA.
Am J Clin Dermatol. 2024 May;25(3):465-471. doi: 10.1007/s40257-024-00851-6. Epub 2024 Mar 7.
Acne is one of the most common dermatological conditions to affect women of childbearing age, so it is important to consider the safety of long-term acne treatments on women who could become pregnant. In this review article, we clarify what management options are available to treat acne during pregnancy. Topical treatments, typically first-line for acne, such as azelaic acid, clindamycin, erythromycin, metronidazole, benzoyl peroxide, salicylic acid, dapsone, and retinoids, were reviewed. Systemic treatments, such as zinc supplements, cephalexin, cefadroxil, amoxicillin, azithromycin, erythromycin, and corticosteroids, typically second-line for acne, were also reviewed. Alternative treatments such as light therapy and cosmetic procedures were also evaluated. Due to recommendation of sunscreen utilization during acne treatments, sunscreen usage during pregnancy was also assessed. Management of acne during unplanned pregnancy was discussed in further detail regarding safety and adverse effects. Through summarized tables and examples of studies demonstrating safety and efficacy of treatments, the following is a resource for providers and patients to utilize for management of acne during pregnancy.
痤疮是影响育龄期女性最常见的皮肤病之一，因此，对于那些可能怀孕的女性，考虑长期痤疮治疗的安全性非常重要。在这篇综述文章中，我们阐明了在怀孕期间可用于治疗痤疮的管理选择。我们回顾了局部治疗方法，如壬二酸、克林霉素、红霉素、甲硝唑、过氧化苯甲酰、水杨酸、达帕胺和类视黄醇，这些方法通常是痤疮的一线治疗方法。我们还回顾了系统治疗方法，如锌补充剂、头孢氨苄、头孢羟氨苄、阿莫西林、阿奇霉素、红霉素和皮质类固醇，这些方法通常是痤疮的二线治疗方法。我们还评估了光疗和美容程序等替代治疗方法。由于建议在痤疮治疗期间使用防晒霜，因此还评估了怀孕期间使用防晒霜的情况。我们进一步详细讨论了意外怀孕时痤疮的管理，讨论了安全性和不良反应。通过总结表格和展示治疗安全性和疗效的研究示例，为提供者和患者提供了管理怀孕期间痤疮的资源。
