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基于氢氧化钙的根管内药物与三种不同载体(蜂胶、壳聚糖和丙二醇)联合使用时钙离子释放和扩散能力的比较。

An comparison of calcium ions release and diffusion ability of calcium hydroxide-based intracanal medicament in combination with three different vehicles like propolis, chitosan, and propylene glycol.

作者信息

Thomas Pinku T, Issac Jyoti Sumi, Girija Parvathy, Chandran Lekshmi S, Arjun D S, Siddik A J

机构信息

Department of Pediatric and Preventive Dentistry, Azeezia College of Dental Sciences and Research, Kollam, Kerala, India.

出版信息

J Conserv Dent Endod. 2024 Feb;27(2):190-194. doi: 10.4103/JCDE.JCDE_258_23. Epub 2024 Feb 8.

DOI:10.4103/JCDE.JCDE_258_23
PMID:38463473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10923230/
Abstract

CONTEXT

Calcium hydroxide, which is an intracanal medicament, is widely used in endodontics. Improvements can be made to its effectiveness, as calcium hydroxide is dependent on the vehicle.

AIM

The study aims to compare and evaluate the release and diffusion ability of calcium hydroxide when mixed with - propolis, chitosan, and propylene glycol.

METHODS

For this study, 33 single-rooted extracted premolar teeth have been decoronated. After the working length and enlargement of the canals had been established, different preparations of calcium hydroxide with vehicles such as propolis, chitosan, and propylene glycol were loaded into the canals. Atomic absorption spectrophotometry was used to analyze the release of calcium ions in three groups, while a digital pH meter was used to determine an acid change.

RESULTS

Atomic absorption spectrophotometry showed sustained releases of calcium ions and the digital pH meter showed increased diffusion capacity in the propylene glycol paste group in comparison to the other two groups.

CONCLUSION

Propylene glycol vehicle made it easier to enter calcium hydroxide into the dentinal tubules.

摘要

背景

氢氧化钙作为一种根管内药物,在牙髓病学中被广泛应用。由于氢氧化钙的有效性取决于载体,因此可以对其进行改进。

目的

本研究旨在比较和评估氢氧化钙与蜂胶、壳聚糖和丙二醇混合时的释放和扩散能力。

方法

在本研究中,对33颗单根拔除的前磨牙进行了去冠处理。确定根管工作长度并扩大根管后,将不同的含蜂胶、壳聚糖和丙二醇等载体的氢氧化钙制剂载入根管。采用原子吸收分光光度法分析三组中钙离子的释放情况,同时使用数字pH计测定酸碱度变化。

结果

原子吸收分光光度法显示钙离子持续释放,数字pH计显示与其他两组相比,丙二醇糊剂组的扩散能力增强。

结论

丙二醇载体使氢氧化钙更容易进入牙本质小管。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dea9/10923230/ebf6a72baaa7/JCDE-27-190-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dea9/10923230/d7f181a3cacc/JCDE-27-190-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dea9/10923230/be8d3c6c7895/JCDE-27-190-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dea9/10923230/5d2dc2f88332/JCDE-27-190-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dea9/10923230/ebf6a72baaa7/JCDE-27-190-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dea9/10923230/d7f181a3cacc/JCDE-27-190-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dea9/10923230/be8d3c6c7895/JCDE-27-190-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dea9/10923230/5d2dc2f88332/JCDE-27-190-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dea9/10923230/ebf6a72baaa7/JCDE-27-190-g005.jpg

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