Nadar Ashima, Muliya Vidya Saraswathi, Pai Swathi, Pentapati Kalyana Chakravarthy
Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Department of Conservative Dentistry and Endodontics, KVG Dental College and Hospital, Sullia, Karnataka, India.
J Conserv Dent. 2023 Jan-Feb;26(1):47-51. doi: 10.4103/jcd.jcd_387_22. Epub 2022 Dec 8.
Nano-calcium hydroxide (NCH) has been proven to have several advantages over normal calcium hydroxide, supporting in its possible use as an intracanal medicament.
The aim is to evaluate and compare calcium ion release and pH change using NCH with different vehicles as intracanal medicament.
Sixty freshly extracted premolars were decoronated at the cementoenamel junction level and the length was standardized. Canals were enlarged to F3 size using protaper rotary system. The samples were divided into three groups ( = 20), namely NCH + distilled water (Group 1), NCH + propylene glycol (Group 2), and NCH + chitosan (CT) (Group 3). Each sample was suspended in 6 ml of distilled water using silicone putty with only the apical third of the roots immersed. The pH and calcium ions were assessed at 24 h, 7 days, 15 days, and 30 days using a pH meter and ultraviolet spectrophotometer, respectively.
Comparison of mean calcium release and pH change was made using Kruskal-Wallis ANOVA with Dunn's test. The level of significance was set at 5%.
A significant difference was seen in the calcium ion release and pH change among the three groups at 24 h, 7 days, 15 days, and 30 days.
NCH mixed with propylene glycol showed alkaline pH and adequate release of calcium ions till 30 days. NCH mixed with CT exhibited a high pH at the end of 30 days. Both combinations proved their efficacy as intracanal medicaments.
纳米氢氧化钙（NCH）已被证明比普通氢氧化钙具有多种优势，这支持了其作为根管内药物的潜在用途。
旨在评估和比较使用不同载体的NCH作为根管内药物时的钙离子释放和pH变化。
60颗新鲜拔除的前磨牙在牙骨质釉质界水平截冠，并将长度标准化。使用Protaper旋转系统将根管扩大至F3尺寸。样本分为三组（每组n = 20），即NCH + 蒸馏水（第1组）、NCH + 丙二醇（第2组）和NCH + 壳聚糖（CT）（第3组）。每个样本用硅酮腻子悬浮在6 ml蒸馏水中，仅使根尖三分之一浸入水中。分别在24小时、7天、15天和30天使用pH计和紫外分光光度计评估pH值和钙离子。
使用Kruskal-Wallis方差分析和Dunn检验比较平均钙释放量和pH变化。显著性水平设定为5%。
在24小时、7天、15天和30天时，三组之间的钙离子释放和pH变化存在显著差异。
与丙二醇混合的NCH在30天内显示出碱性pH值和足够的钙离子释放。与CT混合的NCH在30天结束时表现出高pH值。两种组合均证明了其作为根管内药物的有效性。
