Marquez-Romero Juan Manuel, Romo-Martínez Jessica, Hernández-Curiel Bernardo, Ruiz-Franco Angélica, Krishnamurthi Rita, Feigin Valery
Instituto Mexicano del Seguro Social, Órgano de Operación Administrativa Desconcentrada, Hospital General de Zona #2, Departamento de Neurología, Aguascalientes AGS, Mexico.
Instituto Mexicano del Seguro Social, Órgano de Operación Administrativa Desconcentrada, Centro Médico de Occidente, Departamento de Radiología, Guadalajara JAL, Mexico.
Arq Neuropsiquiatr. 2024 Mar;82(3):1-5. doi: 10.1055/s-0044-1779691. Epub 2024 Mar 11.
Genetic factors influence the risk of developing stroke. Still, it is unclear whether this risk is intrinsically high in certain people or if nongenetic factors explain it entirely.
To compare the risk of stroke in kin and nonkin caregivers.
In a cross-sectional study using the Stroke Riskometer app (AUT Ventures Limited, Auckland, AUK, New Zealand), we determined the 5- and 10-year stroke risk (SR) among caregivers of stroke inpatients. The degree of kinship was rated with a score ranging from 0 to 50 points.
We studied 278 caregivers (69.4% of them female) with a mean age of 47.5 ± 14.2 years. Kin caregivers represented 70.1% of the sample, and 49.6% of them were offspring. The median SR at 5 years was of 2.1 (range: 0.35-17.3) versus 1.73 (range: 0.04-29.9), and of 4.0 (range: 0.45-38.6) versus 2.94 (range: 0.05-59.35) at 10 years for the nonkin and kin caregivers respectively. In linear logistic regression controlled for the age of the caregivers, adding the kinship score did not increase the overall variability of the model for the risk at 5 years (R= 0.271; = 0.858) nor the risk at 10 years (R= 0.376; = 0.78).
Caregivers of stroke patients carry a high SR regardless of their degree of kinship.
遗传因素会影响中风发病风险。然而,尚不清楚某些人群的这种风险是否本质上就很高,或者非遗传因素是否能完全解释这一现象。
比较亲属照料者和非亲属照料者的中风风险。
在一项横断面研究中,我们使用中风风险评估应用程序(新西兰奥克兰AUT Ventures Limited公司),确定了中风住院患者照料者的5年和10年中风风险(SR)。亲属关系程度通过0至50分的评分来确定。
我们研究了278名照料者(其中69.4%为女性),平均年龄为47.5±14.2岁。亲属照料者占样本的70.1%,其中49.6%为后代。非亲属照料者和亲属照料者的5年中风风险中位数分别为2.1(范围:0.35 - 17.3)和1.73(范围:0.04 - 29.9),10年中风风险中位数分别为4.0(范围:0.45 - 38.6)和2.94(范围:0.05 - 59.35)。在对照料者年龄进行控制的线性逻辑回归分析中,加入亲属关系评分并未增加模型在5年风险(R = 0.271;P = 0.858)或10年风险(R = 0.376;P = 0.78)方面的总体变异性。
中风患者的照料者,无论其亲属关系程度如何,中风风险都很高。