Brown Jacob T, Sorge Lindsay A, Oetting William S, Jacobson Pamala A, Pereira Chrystian
University of Minnesota, College of Pharmacy.
Innov Pharm. 2023 Nov 20;14(4). doi: 10.24926/iip.v14i4.5142. eCollection 2023.
: Pharmacogenomics (PGx) is increasingly being used for creating individualized treatments for patient care. Healthcare professionals, especially pharmacists, need to understand how genetic variation impacts the efficacy and toxicity of medications. Due to the breadth and complexity of PGx-related information, it has been challenging to determine what information should be included in pharmacy curricula and how best to educate students. : The University of Minnesota College of Pharmacy recently began the process of incorporating into the curriculum expanded competencies for PGx from the American Association of Colleges of Pharmacy (AACP) Pharmacogenomics Special Interest Group (PGx-SIG). We evaluated our curriculum for PGx content, determined what was currently being taught and identified educational gaps. : A review of our Doctor of Pharmacy curriculum showed substantial PGx content, although it was inconsistently taught throughout the required courses and in some courses absent. We revised the content of existing courses incorporating content that meet most of the PGx-SIG recommended competencies. : There are and will be major changes in our understanding of the influences of PGx on individualized medical treatment. As our understanding grows, information on PGx in pharmacy curriculums will need to keep pace with these changes. We have begun this process at the University of Minnesota by doing a full review of PGx related information and making appropriate revisions in the pharmacy curriculum.
药物基因组学(PGx)越来越多地被用于为患者护理制定个性化治疗方案。医疗保健专业人员,尤其是药剂师,需要了解基因变异如何影响药物的疗效和毒性。由于PGx相关信息的广度和复杂性,确定药学课程应包含哪些信息以及如何最好地教育学生一直具有挑战性。
明尼苏达大学药学院最近开始将美国药学院协会(AACP)药物基因组学特别兴趣小组(PGx-SIG)的PGx扩展能力纳入课程的过程。我们评估了我们的PGx课程内容,确定了目前正在教授的内容,并找出了教育差距。
对我们药学博士课程的审查显示,虽然PGx内容在必修课程中讲授不一致,在一些课程中甚至没有,但内容相当丰富。我们修订了现有课程的内容,纳入了符合PGx-SIG大多数推荐能力的内容。
我们对PGx对个性化医疗影响的理解现在和将来都会有重大变化。随着我们理解的加深,药学课程中关于PGx的信息将需要跟上这些变化。我们在明尼苏达大学已经通过全面审查PGx相关信息并在药学课程中进行适当修订开始了这一进程。