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对木麻黄不同提取物的植物化学分析及其抗氧化、抗菌和细胞毒性活性评价。

Phytochemical analysis and evaluation of its antioxidant, antimicrobial, and cytotoxic activities for different extracts of Casuarina equisetifolia.

机构信息

Chemistry of Medicinal Plants Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, 33 El Buhouth St. (FormerEl Tahrir St.), Dokki, Giza, 12622, Egypt.

Physical Chemistry Department, Electrochemistry and Corrosion Lab, National Research Centre, El-Bohouth St. 33, Dokki, Giza, 12622, Egypt.

出版信息

BMC Complement Med Ther. 2024 Mar 20;24(1):128. doi: 10.1186/s12906-024-04422-4.

DOI:10.1186/s12906-024-04422-4
PMID:38509538
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10956242/
Abstract

BACKGROUND

Casuarina equisetifolia belongs to the Casuarina species with the most extensive natural distribution, which contain various phytochemicals with potential health benefits. This study aimed to investigate the chemical composition and biological activities of different extracts of Casuarina equisetifolia.

METHODS

The n-hexane extract was analyzed for its unsaponifiable and fatty acid methyl esters fractions, while chloroform, ethyl acetate, and butanol extracts were studied for their phenolic components. Six different extracts of C. equisetifolia needles were evaluated for their total phenolic content, total flavonoid content, and their antioxidant, antimicrobial, and cytotoxic activities.

RESULTS

The n-hexane extract contained mainly hydrocarbons and fatty acid methyl esters, while ten phenolic compounds were isolated and identified in the chloroform, ethyl acetate, and butanol extracts. The methanolic extract exhibited the highest total phenolic and flavonoid content, highest antioxidant activity, and most potent cytotoxic activity against HepG-2 and HCT-116 cancer cell lines. The ethyl acetate extract showed the most significant inhibition zone against Staphylococcus aureus and Bacillus subtilis.

CONCLUSION

Casuarina equisetifolia extracts showed promising antioxidant, antimicrobial, and cytotoxic activities. Overall, Casuarina equisetifolia is a versatile tree with a variety of uses, and its plant material can be used for many different purposes.

摘要

背景

木麻黄属于木麻黄属，具有最广泛的自然分布，其中含有各种具有潜在健康益处的植物化学成分。本研究旨在研究木麻黄不同提取物的化学成分和生物活性。

方法

分析了正己烷提取物的不可皂化物和脂肪酸甲酯部分，而氯仿、乙酸乙酯和正丁醇提取物则研究了其酚类成分。评估了木麻黄针叶的六种不同提取物的总酚含量、总黄酮含量以及抗氧化、抗菌和细胞毒性活性。

结果

正己烷提取物主要含有碳氢化合物和脂肪酸甲酯，而在氯仿、乙酸乙酯和正丁醇提取物中分离和鉴定了十种酚类化合物。甲醇提取物表现出最高的总酚和总黄酮含量、最高的抗氧化活性以及对 HepG-2 和 HCT-116 癌细胞系最强的细胞毒性活性。乙酸乙酯提取物对金黄色葡萄球菌和枯草芽孢杆菌的抑制圈最大。

结论

木麻黄提取物表现出有希望的抗氧化、抗菌和细胞毒性活性。总的来说，木麻黄是一种用途广泛的多功能树，其植物材料可用于许多不同的用途。

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本文引用的文献

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Heliyon. 2021 Nov 14;7(11):e08397. doi: 10.1016/j.heliyon.2021.e08397. eCollection 2021 Nov.
2
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3
Therapeutic Potential of Plant Phenolic Acids in the Treatment of Cancer.植物酚酸类化合物在癌症治疗中的治疗潜力。
Biomolecules. 2020 Feb 3;10(2):221. doi: 10.3390/biom10020221.
4
Antitumor Effects of Quercetin in Hepatocarcinoma In Vitro and In Vivo Models: A Systematic Review.槲皮素在肝癌体外和体内模型中的抗肿瘤作用：系统评价。
Nutrients. 2019 Nov 25;11(12):2875. doi: 10.3390/nu11122875.
5
Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects.槲皮素在抗癌作用方面的药理基础和新见解。
Biomed Pharmacother. 2020 Jan;121:109604. doi: 10.1016/j.biopha.2019.109604. Epub 2019 Nov 13.
6
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7
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Nutr Cancer. 2018 May-Jun;70(4):594-604. doi: 10.1080/01635581.2018.1460679. Epub 2018 Apr 25.
8
Apigenin in cancer therapy: anti-cancer effects and mechanisms of action.芹菜素在癌症治疗中的作用：抗癌效果及作用机制
Cell Biosci. 2017 Oct 5;7:50. doi: 10.1186/s13578-017-0179-x. eCollection 2017.
9
Isolation and identification of flavonoids components from L.从L.中分离和鉴定黄酮类成分
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10
Medicinal Plants: Their Use in Anticancer Treatment.药用植物：它们在抗癌治疗中的应用。
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