Chemistry of Medicinal Plants Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, 33 El Buhouth St. (FormerEl Tahrir St.), Dokki, Giza, 12622, Egypt.
Physical Chemistry Department, Electrochemistry and Corrosion Lab, National Research Centre, El-Bohouth St. 33, Dokki, Giza, 12622, Egypt.
BMC Complement Med Ther. 2024 Mar 20;24(1):128. doi: 10.1186/s12906-024-04422-4.
Casuarina equisetifolia belongs to the Casuarina species with the most extensive natural distribution, which contain various phytochemicals with potential health benefits. This study aimed to investigate the chemical composition and biological activities of different extracts of Casuarina equisetifolia.
The n-hexane extract was analyzed for its unsaponifiable and fatty acid methyl esters fractions, while chloroform, ethyl acetate, and butanol extracts were studied for their phenolic components. Six different extracts of C. equisetifolia needles were evaluated for their total phenolic content, total flavonoid content, and their antioxidant, antimicrobial, and cytotoxic activities.
The n-hexane extract contained mainly hydrocarbons and fatty acid methyl esters, while ten phenolic compounds were isolated and identified in the chloroform, ethyl acetate, and butanol extracts. The methanolic extract exhibited the highest total phenolic and flavonoid content, highest antioxidant activity, and most potent cytotoxic activity against HepG-2 and HCT-116 cancer cell lines. The ethyl acetate extract showed the most significant inhibition zone against Staphylococcus aureus and Bacillus subtilis.
Casuarina equisetifolia extracts showed promising antioxidant, antimicrobial, and cytotoxic activities. Overall, Casuarina equisetifolia is a versatile tree with a variety of uses, and its plant material can be used for many different purposes.
木麻黄属于木麻黄属，具有最广泛的自然分布，其中含有各种具有潜在健康益处的植物化学成分。本研究旨在研究木麻黄不同提取物的化学成分和生物活性。
分析了正己烷提取物的不可皂化物和脂肪酸甲酯部分，而氯仿、乙酸乙酯和正丁醇提取物则研究了其酚类成分。评估了木麻黄针叶的六种不同提取物的总酚含量、总黄酮含量以及抗氧化、抗菌和细胞毒性活性。
正己烷提取物主要含有碳氢化合物和脂肪酸甲酯，而在氯仿、乙酸乙酯和正丁醇提取物中分离和鉴定了十种酚类化合物。甲醇提取物表现出最高的总酚和总黄酮含量、最高的抗氧化活性以及对 HepG-2 和 HCT-116 癌细胞系最强的细胞毒性活性。乙酸乙酯提取物对金黄色葡萄球菌和枯草芽孢杆菌的抑制圈最大。
木麻黄提取物表现出有希望的抗氧化、抗菌和细胞毒性活性。总的来说，木麻黄是一种用途广泛的多功能树，其植物材料可用于许多不同的用途。
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