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一名绝经后女性的原发性右肾上腺畸胎瘤:病例报告及文献综述

Primary Right Adrenal Teratoma in a Postmenopausal Female: a Case Report and Review of Literature.

作者信息

Singh Utkarsh, Roy Shubhajeet, Gaurav Kushagra, Anand Akshay, Sonkar Abhinav A

机构信息

Faculty of Medical Sciences, King George's Medical University, Lucknow, Uttar Pradesh India.

Department of General Surgery, King George's Medical University, Shah Mina Shah Road, Chowk, Lucknow, Uttar Pradesh 226003 India.

出版信息

Indian J Surg Oncol. 2024 Mar;15(1):185-192. doi: 10.1007/s13193-023-01863-0. Epub 2023 Dec 16.

Abstract

Non-seminomatous germ cell tumors with structural components from all three cellular lineages are called teratomas. We report a rare case of a primary right adrenal teratoma in a postmenopausal female, presenting with abdominal pain. Ultrasound revealed a complex cystic shadow in the perihepatic region superior to the upper pole of the right kidney, which was suggestive of a complex supra-renal space-sequence-occupying lesion. Computerized tomography revealed a large-sized mature single multilobulated complex cystic lesion in the right hypochondrial lumbar region arising from the right adrenal gland. A right-sided transperitoneal adrenalectomy was performed. The resected mass (18 × 13 × 10 cm) was well encapsulated. Cut surfaces showed cystic mass filled with necrotic gray-white pultaceous material, along with a solid white gelatinous area. Microscopic sections showed a tumor which displayed differentiation along various tissue lineages. After immunohistochemical examinations, the tumor was confirmed to be a mature cystic teratoma. Mature teratomas show a good prognosis, and surgical resection and follow-up remain the standard approach.

摘要

具有来自所有三个细胞谱系结构成分的非精原性生殖细胞肿瘤被称为畸胎瘤。我们报告了一例罕见的绝经后女性原发性右肾上腺畸胎瘤病例,该患者表现为腹痛。超声显示右肾上极上方肝周区域有一个复杂的囊性阴影,提示为肾上腺区复杂占位性病变。计算机断层扫描显示右季肋部腰区有一个由右肾上腺产生的大尺寸成熟单叶多房性复杂囊性病变。进行了右侧经腹肾上腺切除术。切除的肿块(18×13×10厘米)包膜完整。切面显示囊性肿块,内充满坏死的灰白色豆腐渣样物质,还有一个实性白色胶冻样区域。显微镜切片显示肿瘤呈现沿各种组织谱系的分化。免疫组化检查后,肿瘤被确诊为成熟囊性畸胎瘤。成熟畸胎瘤预后良好,手术切除及随访仍是标准的治疗方法。

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本文引用的文献

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Primary adrenal teratoma: An unusual tumor - Challenges in diagnosis and surgical management.
J Postgrad Med. 2018 Apr-Jun;64(2):112-114. doi: 10.4103/jpgm.JPGM_588_16.
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Adrenal Teratoma: a Case Series and Review of the Literature.
Endocr Pathol. 2017 Jun;28(2):152-158. doi: 10.1007/s12022-017-9468-5.
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Primary adrenal teratoma: Clinical characteristics and retroperitoneal laparoscopic resection in five adults.
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