Seo Jegak, Kloprogge Frank, Smith Andrew M, Karu Kersti, Ciric Lena
Healthy Infrastructure Research Group, Department of Civil, Environmental and Geomatic Engineering, University College London, Gower Street, London WC1E 6BT, UK.
Institute for Global Health, University College London, Rowland Hill Street, London NW3 2PF, UK.
Toxics. 2024 Feb 24;12(3):174. doi: 10.3390/toxics12030174.
While the use of antibiotics has been reported as extensive in the rearing of agricultural animals, insufficient information is available on the antibiotic residues in animal products and the adverse impact that consistent low-level exposure to antibiotics might have on the human body and its microbiome. The aim of this study was to estimate the antibiotic concentrations that humans are exposed to via their diet using the concentration of antibiotics in animal food products and water and an online survey on dietary intake. A total of 131 participants completed the dietary intake survey, with the majority belonging to the omnivorous diet group (76.3%). Distinct dietary trends were observed in the omnivorous and unknown groups eating animal products, with specific food types dominating each meal: pork (e.g., ham) and dairy products (e.g., milk, yoghurt) during breakfast, beef (e.g., burgers) and chicken (e.g., chicken breast) products during lunch, and fish (e.g., salmon fillet) during dinner. In total, 34 different animal-based food and drink products were tested for the presence of ten different antibiotics. Of all the products tested, over 35% exceeded the acceptable daily antibiotic intake for amoxicillin, ampicillin, and enrofloxacin.
虽然在农业动物饲养中抗生素的使用已被广泛报道,但关于动物产品中的抗生素残留以及持续低水平接触抗生素可能对人体及其微生物群产生的不利影响,目前可获得的信息不足。本研究的目的是利用动物食品和水中的抗生素浓度以及一项关于饮食摄入量的在线调查,来估计人类通过饮食接触到的抗生素浓度。共有131名参与者完成了饮食摄入量调查,其中大多数属于杂食饮食组(76.3%)。在食用动物产品的杂食组和饮食情况不明的组中观察到了不同的饮食趋势,每餐都有特定的食物类型占主导:早餐时是猪肉(如火腿)和乳制品(如牛奶、酸奶),午餐时是牛肉(如汉堡)和鸡肉(如鸡胸肉)产品,晚餐时是鱼类(如三文鱼片)。总共对34种不同的动物性食品和饮料产品进行了10种不同抗生素的检测。在所有检测的产品中,超过35%的产品阿莫西林、氨苄青霉素和恩诺沙星的每日抗生素摄入量超过了可接受水平。