Xu Chunming, Kong Lingqiang, Gao Hanfang, Cheng Xiyu, Wang Xiumin
School of Light Industry, Beijing Technology and Business University, Beijing, China.
Key Laboratory of Cleaner Production and Integrated Resource Utilization of China National Light Industry, Beijing Technology and Business University, Beijing, China.
Front Microbiol. 2022 May 12;13:822689. doi: 10.3389/fmicb.2022.822689. eCollection 2022.
The overuse of antibiotics in food animals has led to the development of bacterial resistance and the widespread of resistant bacteria in the world. Antibiotic-resistant bacteria (ARB) and antibiotic-resistant genes (ARGs) in food animals are currently considered emerging contaminants, which are a serious threat to public health globally. The current situation of ARB and ARGs from food animal farms, manure, and the wastewater was firstly covered in this review. Potential risks to public health were also highlighted, as well as strategies (including novel technologies, alternatives, and administration) to fight against bacterial resistance. This review can provide an avenue for further research, development, and application of novel antibacterial agents to reduce the adverse effects of antibiotic resistance in food animal farms.
食用动物中抗生素的过度使用导致了细菌耐药性的产生以及耐药菌在全球范围内的广泛传播。食用动物中的抗生素耐药菌(ARB)和抗生素耐药基因(ARGs)目前被视为新出现的污染物,对全球公共卫生构成严重威胁。本综述首先介绍了来自食用动物养殖场、粪便和废水中ARB和ARGs的现状。还强调了对公共卫生的潜在风险,以及对抗细菌耐药性的策略(包括新技术、替代方法和管理措施)。本综述可为进一步研究、开发和应用新型抗菌剂提供途径,以减少食用动物养殖场抗生素耐药性的不利影响。