Fogt Jennifer Swingle, Satiani Nidhi, Bickle Katherine M, Wesley Gina, Patton Kimberly
College of Optometry, The Ohio State University, Columbus, OH, USA.
Clin Optom (Auckl). 2024 Mar 26;16:93-100. doi: 10.2147/OPTO.S452132. eCollection 2024.
Patients expect to have excellent vision and comfort when wearing soft contact lenses. The purpose of this study was to compare the wear experiences of participants with astigmatism when wearing a daily disposable soft toric lens to an established, commonly used reusable toric lens.
In this crossover study, habitual soft toric lens wearers were fit with a daily replacement soft toric lens (delefilcon A) and a reusable, 1-month replacement soft toric lens (comfilcon A) in a randomized order. After 30 days of wear, Visual analog scale (VAS) surveys were used to assess wear experience, including vision and comfort, for overall wear and end-of-day wear. Scores were compared statistically with mixed-effects linear models. Participants also responded to questions about convenience, ease of use, and satisfaction with both lenses and preference questions based upon comfort, vision, and overall performance.
Fifty-nine participants completed the multi-site crossover study. VAS scores [mean(std dev)] for overall quality of vision for the delefilcon A [80.4(16.4)] and comfilcon A [66.8(27.7)] lenses were statistically significant (P=0.002). The difference in the mean overall comfort scores for the delefilcon A lenses [71.6(26.3)] and comfilcon A lenses [63.2(28.9)] was 8.4, which exceeds the establish criteria for clinical significance, although not statistically significant (P=0.08). Overall satisfaction scores were 68.8(26.9) for the delefilcon A and 59.7(30.3) for the comfilcon A lenses (P=0.08). Both lenses provided mean binocular visual acuities better than 20/20 Snellen equivalent. Over half of the participants preferred the delefilcon A lenses based upon comfort, vision, and overall performance. Convenience, ease of use, and satisfaction all scored higher with delefilcon A lenses.
The results of this study show that wear experience with delefilcon A lenses for astigmatism can meet or exceed that of comfilcon A toric lenses while also providing healthy, daily disposable lens wear.
患者期望佩戴软性隐形眼镜时能拥有出色的视力和舒适度。本研究的目的是比较散光患者佩戴日抛型软性散光隐形眼镜与一种成熟的常用可重复使用散光隐形眼镜时的佩戴体验。
在这项交叉研究中，习惯性佩戴软性散光隐形眼镜的受试者被随机顺序佩戴日抛型软性散光隐形眼镜（delefilcon A）和可重复使用、每月更换一次的软性散光隐形眼镜（comfilcon A）。佩戴30天后，使用视觉模拟量表（VAS）调查评估佩戴体验，包括总体佩戴和每日佩戴结束时的视力和舒适度。使用混合效应线性模型对得分进行统计学比较。受试者还回答了关于便利性、易用性以及对两种镜片的满意度的问题，以及基于舒适度、视力和总体性能的偏好问题。
59名受试者完成了多中心交叉研究。delefilcon A镜片[80.4(16.4)]和comfilcon A镜片[66.8(27.7)]的总体视力质量的VAS评分在统计学上具有显著差异（P = 0.002）。delefilcon A镜片[71.6(26.3)]和comfilcon A镜片[63.2(28.9)]的平均总体舒适度评分差异为8.4，虽无统计学显著性（P = 0.08），但超过了临床意义的既定标准。delefilcon A镜片的总体满意度评分为68.8(26.9)，comfilcon A镜片为59.7(30.3)（P = 0.08）。两种镜片的双眼平均视力均优于20/20 Snellen等效视力。超过一半的受试者基于舒适度、视力和总体性能更喜欢delefilcon A镜片。delefilcon A镜片在便利性、易用性和满意度方面的得分均更高。
本研究结果表明，散光患者佩戴delefilcon A镜片的佩戴体验可以达到或超过comfilcon A散光镜片，同时还能提供健康的日抛型镜片佩戴方式。
