Department of Endocrinology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.
Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.
Diabetes Obes Metab. 2024 Jun;26(6):2456-2465. doi: 10.1111/dom.15568. Epub 2024 Apr 1.
We aimed to assess the global implications of low physical activity (LPA) on type 2 diabetes mellitus (T2DM) by utilizing data from the Global Burden of Disease (GBD) 2019.
The analysis was conducted by examining the age-standardized disability-adjusted life years (DALYs) rates over a 30-year period. To assess the trends, we utilized estimated annual percentage changes (EAPCs).
The study revealed a notable increase in the burden of DALYs attributable to T2DM resulting from LPA, with an EAPC of 0.84 (95% confidence interval 0.78-0.89). Among the regions examined, Oceania showed the highest burden, whereas Eastern Europe exhibited the lowest burden. Specifically, within the Central Asia region, a considerable increase in T2DM-LPA DALYs was observed, with an EAPC of 3.18 (95% confidence interval 3.01-3.36). The burden associated with T2DM-LPA DALYs was found to be similar between genders and increased across all age groups, peaking in the 80-84 years. Furthermore, there was a clear association between the socio-demographic index (SDI) and the age-standardized DALYs rate. Regions categorized as low-middle and middle SDI experienced a substantial rise in burden.
This study highlights a substantial increase in the T2DM-LPA DALYs in low-middle and middle SDI regions, as well as among individuals aged 80-84 years. These findings emphasize the importance of implementing comprehensive global health interventions that promote physical activity, particularly targeting high-risk populations and regions.
利用 2019 年全球疾病负担(GBD)的数据,评估低身体活动(LPA)对 2 型糖尿病(T2DM)的全球影响。
通过分析 30 年来年龄标准化残疾调整生命年(DALYs)率来进行分析。为了评估趋势,我们利用了估计的年百分比变化(EAPCs)。
研究显示,由于 LPA,T2DM 导致的 DALY 负担显著增加,EAPC 为 0.84(95%置信区间 0.78-0.89)。在所检查的区域中,大洋洲的负担最重,东欧的负担最轻。具体而言,在中亚地区,T2DM-LPA DALY 显著增加,EAPC 为 3.18(95%置信区间 3.01-3.36)。T2DM-LPA DALY 相关负担在两性之间相似,并在所有年龄组中增加,在 80-84 岁年龄组达到峰值。此外,T2DM-LPA DALY 与社会人口指数(SDI)之间存在明显关联。SDI 分类为中低和中等的地区负担显著增加。
本研究强调了中低和中等 SDI 地区以及 80-84 岁年龄组 T2DM-LPA DALY 负担的大幅增加。这些发现强调了实施全面全球健康干预措施的重要性,特别是针对高风险人群和地区,以促进身体活动。