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临床医生和家庭护理人员对临终前老年疗养院居民慢性疾病药物减用的看法。

Clinician and Family Caregiver Perspectives on Deprescribing Chronic Disease Medications in Older Nursing Home Residents Near the End of Life.

机构信息

Center for Health Equity Research and Promotion (CHERP), VA Pittsburgh Healthcare System, Research Office Building #30, University Drive (151C), Pittsburgh, PA, 15240, USA.

Veteran Experience Center, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.

出版信息

Drugs Aging. 2024 Apr;41(4):367-377. doi: 10.1007/s40266-024-01110-3. Epub 2024 Apr 4.

Abstract

INTRODUCTION

Nursing home (NH) residents with limited life expectancy (LLE) who are intensely treated for hyperlipidemia, hypertension, or diabetes may benefit from deprescribing.

OBJECTIVE

This study sought to describe NH clinician and family caregiver perspectives on key influences on deprescribing decisions for chronic disease medications in NH residents near the end of life.

METHODS

We recruited family caregivers of veterans who recently died in a Veterans Affairs (VA) NH, known as community living centers (CLCs), and CLC healthcare clinicians (physicians, nurse practitioners, physician assistants, pharmacists, registered nurses). Respondents completed semi-structured interviews about their experiences with deprescribing statin, antihypertensive, and antidiabetic medications for residents near end of life. We conducted thematic analysis of interview transcripts to identify key themes regarding influences on deprescribing decisions.

RESULTS

Thirteen family caregivers and 13 clinicians completed interviews. Key themes included (1) clinicians and caregivers both prefer to minimize drug burden; (2) clinical factors strongly influence deprescribing of chronic disease medications, with differences in how clinicians and caregivers weigh specific factors; (3) caregivers trust and rely on clinicians to make deprescribing decisions; (4) clinicians perceive caregiver involvement and buy-in as essential to deprescribing decisions, which requires time and effort to obtain; and (5) clinicians perceive conflicting care from other clinicians as a barrier to deprescribing.

CONCLUSIONS

Findings suggest a need for efforts to encourage communication with and education for family caregivers of residents with LLE about deprescribing, and to foster better collaboration among clinicians in CLC and non-CLC settings.

摘要

简介

预期寿命有限(LLE)的疗养院(NH)居民,如果对高血脂、高血压或糖尿病进行强化治疗,可能会从去处方中受益。

目的

本研究旨在描述 NH 临床医生和家庭护理人员对影响终末期 NH 居民慢性疾病药物去处方决策的关键因素的看法。

方法

我们招募了最近在退伍军人事务部(VA)NH 去世的退伍军人的家庭护理人员,称为社区生活中心(CLC),以及 CLC 医疗保健临床医生(医生、护士从业者、医师助理、药剂师、注册护士)。受访者完成了关于他们在生命末期为居民去处方他汀类药物、抗高血压药物和抗糖尿病药物的经验的半结构化访谈。我们对访谈记录进行了主题分析,以确定影响去处方决策的关键主题。

结果

13 名家庭护理人员和 13 名临床医生完成了访谈。关键主题包括:(1)临床医生和护理人员都倾向于最大限度地减少药物负担;(2)临床因素强烈影响慢性疾病药物的去处方,临床医生和护理人员对具体因素的重视程度存在差异;(3)护理人员信任并依赖临床医生做出去处方决定;(4)临床医生认为护理人员的参与和认同对去处方决策至关重要,这需要时间和努力来获得;(5)临床医生认为来自其他临床医生的冲突性护理是去处方的障碍。

结论

研究结果表明,需要努力鼓励与 LLE 居民的家庭护理人员进行沟通和教育,以减少处方,并促进 CLC 和非 CLC 环境中临床医生之间更好的协作。

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1
Categorization of deprescribing communication tools: A scoping review.停用药物沟通工具的分类:范围综述。
Basic Clin Pharmacol Toxicol. 2023 Dec;133(6):640-652. doi: 10.1111/bcpt.13886. Epub 2023 May 23.
2
Deprescribing statins, considerations for informed decision making.停用他汀类药物:明智决策的考量因素
J Am Geriatr Soc. 2023 Aug;71(8):2685-2689. doi: 10.1111/jgs.18362. Epub 2023 Apr 21.

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