成人肾结石与饮食摄入：伊朗西南部的一项基于人群的研究。

Kidney stones and dietary intake in adults: a population-based study in southwest Iran.

机构信息

Department of Biostatistics and Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Department of Nutrition, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran.

出版信息

BMC Public Health. 2024 Apr 4;24(1):955. doi: 10.1186/s12889-024-18393-1.

DOI:10.1186/s12889-024-18393-1

PMID:38575950

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10993538/

Abstract

BACKGROUND

The prevalence of kidney stones is on the rise globally. Several risk factors, including lifestyle, contribute to the formation of kidney stones. Nevertheless, there is a contentious debate about the relationship between diet and kidney stones. Therefore, our study aimed to assess the relationship between macronutrients and micronutrients and the formation of kidney stones.

METHODS

This population-based cross-sectional study was conducted in the baseline phase of the Hoveyzeh Cohort Study, focusing on adults aged 35-70 in southwest Iran. The information on demographic characteristics, anthropometrics, kidney stone history, and food frequency was collected. Chi-square and t-tests were utilized to assess the relationship between categorical and numerical variables with kidney stones. The ANCOVA and logistic regression models were used to evaluate the relationships while controlling for confounding factors.

RESULTS

Among 10,009 participants, the overall prevalence of kidney stones was 18.77% (95% CI: 17.99-19.53). A higher intake of carbohydrates [OR = 1.02 (95% CI:1.002-1.03), p = 0.026] and copper [OR = 1.04 (95% CI:1.01-1.09), p = 0.025] were found to be associated with kidney stones. No associations were found between the other assessed macronutrients or micronutrients and kidney stones (p-tvalues > 0.05).

CONCLUSION

Our study's findings indicate a correlation between diet and the formation of kidney stones. However, the relationship between dietary factors and kidney stones is complex, and further research is needed.

摘要

背景

全球范围内肾结石的患病率呈上升趋势。多种风险因素，包括生活方式，导致肾结石的形成。然而，关于饮食与肾结石之间的关系存在争议。因此，我们的研究旨在评估宏量营养素和微量营养素与肾结石形成之间的关系。

方法

本研究为基于人群的横断面研究，在伊朗西南部的豪韦兹耶 cohort 研究的基线阶段进行，研究对象为 35-70 岁的成年人。收集了人口统计学特征、人体测量学、肾结石史和食物频率等信息。利用卡方检验和 t 检验评估肾结石与分类和数值变量之间的关系。采用协方差分析和逻辑回归模型评估在控制混杂因素的情况下这些关系。

结果

在 10009 名参与者中，肾结石的总体患病率为 18.77%（95%CI：17.99-19.53）。碳水化合物摄入量较高[比值比（OR）=1.02（95%CI：1.002-1.03），p=0.026]和铜摄入量较高[OR=1.04（95%CI：1.01-1.09），p=0.025]与肾结石有关。其他评估的宏量营养素或微量营养素与肾结石之间无关联（p-t 值>0.05）。