Mashberg A, Barsa P, Grossman M L
J Am Dent Assoc. 1985 May;110(5):731-4. doi: 10.14219/jada.archive.1985.0422.
As part of a larger case control study on a male veteran population at risk (drinking and smoking) for oral and pharyngeal cancer, 95 cases and 913 controls provided complete histories in a questionnaire that included data on mouthwash use. Analysis revealed no significant differences in the frequency of mouthwash users in cancer cases versus controls. In addition, no significant differences could be found between users and nonusers of mouthwash in relation to age or smoking and drinking habits. When a logistic regression analysis was performed to simultaneously remove the effects of age, or smoking and drinking habits, while controlling for all other factors, oral and pharyngeal cancer did not appear related to mouthwash use. In this study there is no evidence that mouthwash is a risk factor in the development of oral and pharyngeal cancer in males.
作为一项针对有口腔和咽癌风险（饮酒和吸烟）的男性退伍军人的大型病例对照研究的一部分，95例病例和913名对照者在一份问卷中提供了完整病史，该问卷包括漱口水使用数据。分析显示，癌症病例组和对照组中漱口水使用者的频率没有显著差异。此外，漱口水使用者和非使用者在年龄、吸烟和饮酒习惯方面也没有显著差异。当进行逻辑回归分析以同时消除年龄、吸烟和饮酒习惯的影响，同时控制所有其他因素时，口腔和咽癌似乎与漱口水使用无关。在这项研究中，没有证据表明漱口水是男性口腔和咽癌发生的风险因素。
