Fadulelmola Ahmed, Gregory Rob, Gordon Gavin, Smith Fiona, Jennings Andrew
University Hospital of North Durham, County Durham & Darlington NHSF, Newcastle upon Tyne, UK.
Trauma. 2022 Apr;24(2):109-114. doi: 10.1177/1460408620949725.
A novel virus, SARS-CoV-2, has caused a fatal global pandemic which particularly affects the elderly and those with comorbidities. Hip fractures affect elderly populations, necessitate hospital admissions and place this group at particular risk from COVID-19 infection. This study investigates the effect of COVID-19 infection on 30-day hip fracture mortality.
Data related to 75 adult hip fractures admitted to two units during March and April 2020 were reviewed. The mean age was 83.5 years (range 65-98 years), and most (53, 70.7%) were women. The primary outcome measure was 30-day mortality associated with COVID-19 infection.
The COVID-19 infection rate was 26.7% (20 patients), with a significant difference in the 30-day mortality rate in the COVID-19-positive group (10/20, 50%) compared to the COVID-19-negative group (4/55, 7.3%), with mean time to death of 19.8 days (95% confidence interval: 17.0-22.5). The mean time from admission to surgery was 43.1 h and 38.3 h, in COVID-19-positive and COVID-19-negative groups, respectively. All COVID-19-positive patients had shown symptoms of fever and cough, and all 10 cases who died were hypoxic. Seven (35%) cases had radiological lung findings consistent of viral pneumonitis which resulted in mortality (70% of mortality). 30% ( = 6) contracted the COVID-19 infection in the community, and 70% ( = 14) developed symptoms after hospital admission.
Hip fractures associated with COVID-19 infection have a high 30-day mortality. COVID-19 testing and chest X-ray for patients presenting with hip fractures help in early planning of high-risk surgeries and allow counselling of the patients and family using realistic prognosis.
一种新型病毒,即严重急性呼吸综合征冠状病毒2(SARS-CoV-2),引发了一场致命的全球大流行,尤其对老年人和患有合并症的人影响较大。髋部骨折影响老年人群,需要住院治疗,使这一群体特别容易受到新型冠状病毒肺炎(COVID-19)感染。本研究调查了COVID-19感染对髋部骨折30天死亡率的影响。
回顾了2020年3月至4月期间收治到两个科室的75例成人髋部骨折患者的数据。平均年龄为83.5岁(范围65 - 98岁),大多数(53例,70.7%)为女性。主要结局指标是与COVID-19感染相关的30天死亡率。
COVID-19感染率为26.7%(20例患者),COVID-19阳性组的30天死亡率(10/20,50%)与COVID-19阴性组(4/55,7.3%)相比有显著差异,平均死亡时间为19.8天(95%置信区间:17.0 - 22.5)。COVID-19阳性组和COVID-19阴性组从入院到手术的平均时间分别为43.1小时和38.3小时。所有COVID-19阳性患者均出现发热和咳嗽症状,死亡的10例患者均有缺氧症状。7例(35%)患者有符合病毒性肺炎的肺部影像学表现,这些患者死亡(占死亡病例的70%)。30%(=6例)在社区感染COVID-19,70%(=14例)在入院后出现症状。
与COVID-19感染相关的髋部骨折30天死亡率很高。对髋部骨折患者进行COVID-19检测和胸部X线检查有助于早期规划高风险手术,并能根据实际预后情况为患者及其家属提供咨询。