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新型冠状病毒肺炎感染对髋部骨折30天死亡率的影响。

The impact of COVID-19 infection on hip fracture 30-day mortality.

作者信息

Fadulelmola Ahmed, Gregory Rob, Gordon Gavin, Smith Fiona, Jennings Andrew

机构信息

University Hospital of North Durham, County Durham & Darlington NHSF, Newcastle upon Tyne, UK.

出版信息

Trauma. 2022 Apr;24(2):109-114. doi: 10.1177/1460408620949725.

Abstract

INTRODUCTION

A novel virus, SARS-CoV-2, has caused a fatal global pandemic which particularly affects the elderly and those with comorbidities. Hip fractures affect elderly populations, necessitate hospital admissions and place this group at particular risk from COVID-19 infection. This study investigates the effect of COVID-19 infection on 30-day hip fracture mortality.

METHOD

Data related to 75 adult hip fractures admitted to two units during March and April 2020 were reviewed. The mean age was 83.5 years (range 65-98 years), and most (53, 70.7%) were women. The primary outcome measure was 30-day mortality associated with COVID-19 infection.

RESULTS

The COVID-19 infection rate was 26.7% (20 patients), with a significant difference in the 30-day mortality rate in the COVID-19-positive group (10/20, 50%) compared to the COVID-19-negative group (4/55, 7.3%), with mean time to death of 19.8 days (95% confidence interval: 17.0-22.5). The mean time from admission to surgery was 43.1 h and 38.3 h, in COVID-19-positive and COVID-19-negative groups, respectively. All COVID-19-positive patients had shown symptoms of fever and cough, and all 10 cases who died were hypoxic. Seven (35%) cases had radiological lung findings consistent of viral pneumonitis which resulted in mortality (70% of mortality). 30% ( = 6) contracted the COVID-19 infection in the community, and 70% ( = 14) developed symptoms after hospital admission.

CONCLUSION

Hip fractures associated with COVID-19 infection have a high 30-day mortality. COVID-19 testing and chest X-ray for patients presenting with hip fractures help in early planning of high-risk surgeries and allow counselling of the patients and family using realistic prognosis.

摘要

引言

一种新型病毒,即严重急性呼吸综合征冠状病毒2(SARS-CoV-2),引发了一场致命的全球大流行,尤其对老年人和患有合并症的人影响较大。髋部骨折影响老年人群,需要住院治疗,使这一群体特别容易受到新型冠状病毒肺炎(COVID-19)感染。本研究调查了COVID-19感染对髋部骨折30天死亡率的影响。

方法

回顾了2020年3月至4月期间收治到两个科室的75例成人髋部骨折患者的数据。平均年龄为83.5岁(范围65 - 98岁),大多数(53例,70.7%)为女性。主要结局指标是与COVID-19感染相关的30天死亡率。

结果

COVID-19感染率为26.7%(20例患者),COVID-19阳性组的30天死亡率(10/20,50%)与COVID-19阴性组(4/55,7.3%)相比有显著差异,平均死亡时间为19.8天(95%置信区间:17.0 - 22.5)。COVID-19阳性组和COVID-19阴性组从入院到手术的平均时间分别为43.1小时和38.3小时。所有COVID-19阳性患者均出现发热和咳嗽症状,死亡的10例患者均有缺氧症状。7例(35%)患者有符合病毒性肺炎的肺部影像学表现,这些患者死亡(占死亡病例的70%)。30%(=6例)在社区感染COVID-19,70%(=14例)在入院后出现症状。

结论

与COVID-19感染相关的髋部骨折30天死亡率很高。对髋部骨折患者进行COVID-19检测和胸部X线检查有助于早期规划高风险手术,并能根据实际预后情况为患者及其家属提供咨询。

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