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新型冠状病毒肺炎感染对髋部骨折30天死亡率的影响。

The impact of COVID-19 infection on hip fractures 30-day mortality.

作者信息

Fadulelmola Ahmed, Gregory Rob, Gordon Gavin, Smith Fiona, Jennings Andrew

机构信息

University Hospital of North Durham, County Durham & Darlington NHSF, Newcastle upon Tyne, UK.

出版信息

Trauma. 2021 Oct;23(4):295-300. doi: 10.1177/1460408620951352.

Abstract

INTRODUCTION

A novel virus, SARS-CoV-2 has caused a fatal global pandemic which particularly affects the elderly and those with co-morbidities. Hip fractures affect elderly populations, necessitate hospital admissions, and place this group at particular risk from COVID-19 infection. This study investigates the effect of COVID-19 infection on 30-day hip fracture mortality.

METHOD

Data related to seventy-five adult hip fractures admitted to two units during March and April 2020 was reviewed. The mean age was 83.5 years (range 65-98 years) and most (53, 70.7%) were females. The primary outcome measure was 30-day mortality associated with COVID-19 infection.

RESULTS

The COVID-19 infection rate was 26.7% (20 patients), with a significant difference in the 30-day mortality rate in COVID-19 positive group (10/20, 50%) compared to COVID-19 negative group (4/55, 7.3%), with mean time to death of 19.8 days (95% confidence interval 17.0-22.5). The mean time from admission to surgery was 43.1 hours and 38.3 hours, in COVID-19 positive and COVID-19 negative groups, respectively. All COVID-19 positive patients had shown symptoms of fever and cough, and all ten cases who died were from hypoxia. Seven (35%) cases had radiological lung findings consistent with viral pneumonitis which resulted in mortality (70% of mortality). 30% (n = 6) contracted the COVID-19 infection in the community and 70% (n = 14) developed symptoms after hospital admission.

CONCLUSION

Hip fractures associated with COVID-19 infection have a high 30-day mortality. COVID-19 testing and chest x-ray for patients presenting with hip fractures, helps in early planning of high-risk surgeries and allows counselling of the patients and family using realistic prognosis.

摘要

引言

一种新型病毒——严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引发了一场致命的全球大流行,尤其对老年人和患有合并症的人影响较大。髋部骨折影响老年人群,需要住院治疗,使该群体特别容易受到新型冠状病毒肺炎(COVID-19)感染。本研究调查了COVID-19感染对髋部骨折30天死亡率的影响。

方法

回顾了2020年3月至4月期间收治到两个科室的75例成人髋部骨折相关数据。平均年龄为83.5岁(范围65 - 98岁),大多数(53例,70.7%)为女性。主要结局指标是与COVID-19感染相关的30天死亡率。

结果

COVID-19感染率为26.7%(20例患者),COVID-19阳性组的30天死亡率(10/20,50%)与COVID-19阴性组(4/55,7.3%)相比有显著差异,平均死亡时间为19.8天(95%置信区间17.0 - 22.5)。COVID-19阳性组和COVID-19阴性组从入院到手术的平均时间分别为43.1小时和38.3小时。所有COVID-19阳性患者均出现发热和咳嗽症状,所有死亡的10例均死于缺氧。7例(35%)病例有与病毒性肺炎相符的肺部影像学表现,这些病例导致了死亡(占死亡病例的70%)。30%(n = 6)在社区感染了COVID-19,70%(n = 14)在入院后出现症状。

结论

与COVID-19感染相关的髋部骨折30天死亡率很高。对髋部骨折患者进行COVID-19检测和胸部X光检查,有助于早期规划高风险手术,并能根据实际预后情况为患者及其家属提供咨询。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b412/7457007/36315e873734/10.1177_1460408620951352-fig1.jpg

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