Garfinkel L, Auerbach O, Joubert L
J Natl Cancer Inst. 1985 Sep;75(3):463-9.
In a case-control study in 4 hospitals from 1971 to 1981, 134 cases of lung cancer and 402 cases of colon-rectum cancer (the controls) were identified in nonsmoking women. All cases and controls were confirmed by histologic review of slides, and nonsmoking status and exposures were verified by interview. Odds ratios (OR) increased with increasing number of cigarettes smoked by the husband, particularly for cigarettes smoked at home. The OR for women whose husbands smoked 20 or more cigarettes at home was 2.11 (95% confidence limits: 1.13, 3.95). A logistic regression analysis showed a significant positive trend of increasing risk with increased exposure to the husband's smoking at home, controlled for age, hospital, socioeconomic class, and year of diagnosis. Comparison of women classified by number of hours exposed a day to smoke in the last 5 years and in the last 25 years showed no increase in risk of lung cancer.
在1971年至1981年期间对4家医院进行的一项病例对照研究中，在不吸烟女性中确定了134例肺癌病例和402例结直肠癌病例（对照）。所有病例和对照均通过对切片的组织学检查得以确认，不吸烟状态和暴露情况通过访谈进行核实。比值比（OR）随着丈夫吸烟数量的增加而升高，尤其是在家中吸的香烟。丈夫在家中吸20支或更多香烟的女性的OR为2.11（95%置信区间：1.13，3.95）。逻辑回归分析显示，在控制了年龄、医院、社会经济阶层和诊断年份后，在家中接触丈夫吸烟增加，风险呈显著的正相关趋势。对根据过去5年和过去25年每天接触烟雾的小时数分类的女性进行比较，结果显示肺癌风险没有增加。
