Vail J T, Adler K R, Rothenberg J
Arch Dermatol. 1985 Oct;121(10):1318-20.
Monocytic leukemia may be associated with specific cutaneous changes in about a third of all cases, most characteristically the plum-colored nodule. Nonspecific cutaneous xanthomas have occasionally been reported with a variety of leukemias, mostly in the pediatric literature, but the first report (to our knowledge) of acute myelomonocytic leukemia presenting with specific cutaneous xanthomatous lesions appeared in 1982. Herein is reported a case of chronic myelomonocytic leukemia presenting with a papular histiocytic eruption, and later showing striking cutaneous xanthomas, together with autopsy findings. Physicians should be aware of this rare but important association.
单核细胞白血病在所有病例中约三分之一可能伴有特定的皮肤改变，最典型的是紫红色结节。非特异性皮肤黄色瘤偶尔在各种白血病中有所报道，大多见于儿科文献，但（据我们所知）急性粒单核细胞白血病伴特异性皮肤黄色瘤病变的首例报告出现在1982年。本文报告一例慢性粒单核细胞白血病，其最初表现为丘疹性组织细胞疹，随后出现显著的皮肤黄色瘤，并伴有尸检结果。医生应了解这种罕见但重要的关联。
