Tian Yanlin, Wang Jiaonan, Fang Jianlong, Chen Chen, Zhao Feng, Zhang Yi, Du Peng, Li Yawei, Shi Wanying, Liu Yuanyuan, Ding Enmin, Tang Song, Yue Xu, Shi Xiaoming
Chinese Research Academy of Environmental Sciences, Beijing, China.
Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control (AEMPC), Nanjing University of Information Science & Technology, Nanjing City, Jiangsu Province, China.
China CDC Wkly. 2024 Mar 29;6(13):249-253. doi: 10.46234/ccdcw2024.049.
WHAT IS ALREADY KNOWN ON THIS TOPIC?: Exposure to fine particulate matter (PM) was linked to endocrine hormone disruption in the reproductive system. Nonetheless, it was unclear which specific components of PM were primarily responsible for these associations.
WHAT IS ADDED BY THIS REPORT?: The study presented the initial epidemiological evidence that brief exposure to PM can elevate estradiol levels in postmenopausal women. Various particle components had unique effects, with water-soluble ions and specific inorganic elements like Ag, As, Cd, Hg, Ni, Sb, Se, Sn, and Tl potentially playing significant roles in increasing estradiol levels.
WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: The study established that the prevalence of air pollution, along with its specific components, has been recognized as a novel risk factor affecting the balance of sex hormones.
接触细颗粒物（PM）与生殖系统中的内分泌激素紊乱有关。然而，尚不清楚PM的哪些特定成分主要导致了这些关联。
该研究提供了初步的流行病学证据，即短期接触PM可使绝经后女性的雌二醇水平升高。各种颗粒成分具有独特的作用，水溶性离子以及银、砷、镉、汞、镍、锑、硒、锡和铊等特定无机元素可能在提高雌二醇水平方面发挥重要作用。
该研究证实，空气污染及其特定成分的普遍存在已被视为影响性激素平衡的一个新的风险因素。
