Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University of Lisbon, Caparica, Portugal.
Department of Chemistry, UCIBIO - Applied Molecular Biosciences Unit, NOVA School of Science and Technology, NOVA University Lisbon, Caparica, Portugal.
Appl Environ Microbiol. 2024 Jun 18;90(6):e0175623. doi: 10.1128/aem.01756-23. Epub 2024 May 6.
In the next decades, the increasing material and energetic demand to support population growth and higher standards of living will amplify the current pressures on ecosystems and will call for greater investments in infrastructures and modern technologies. A valid approach to overcome such future challenges is the employment of sustainable bio-based technologies that explore the metabolic richness of microorganisms. Collectively, the metabolic capabilities of , spanning aerobic and anaerobic conditions, thermophilic adaptability, anoxygenic photosynthesis, and utilization of toxic compounds as electron acceptors, underscore the phylum's resilience and ecological significance. These diverse metabolic strategies, driven by the interplay between temperature, oxygen availability, and energy metabolism, exemplify the complex adaptations that enabled to colonize a wide range of ecological niches. In demonstrating the metabolic richness of the phylum, specific members exemplify the diverse capabilities of these microorganisms: showcases adaptability through its thermophilic and phototrophic growth, whereas members of the class are known for their role in the degradation of complex organic compounds, contributing significantly to the carbon cycle in anaerobic environments, highlighting the phylum's potential for biotechnological exploitation in varying environmental conditions. In this context, the metabolic diversity of must be considered a promising asset for a large range of applications. Currently, this bacterial phylum is organized into eight classes possessing different metabolic strategies to survive and thrive in a wide variety of extreme environments. This review correlates the ecological role of in such environments with the potential application of their metabolisms in biotechnological approaches.
在未来几十年，为了支持人口增长和提高生活水平而不断增加的物质和能源需求，将加剧生态系统目前所面临的压力，这将需要在基础设施和现代技术方面投入更多资金。应对这些未来挑战的一种有效方法是采用可持续的基于生物的技术，探索微生物的代谢丰富度。总的来说， 门的微生物具有广泛的代谢能力，包括需氧和厌氧条件、嗜热适应性、非氧光合作用以及利用有毒化合物作为电子受体，这突显了该门的弹性和生态意义。这些多样化的代谢策略是由温度、氧气供应和能量代谢之间的相互作用驱动的，体现了使 门能够广泛适应生态位的复杂适应。通过展示 门的代谢丰富度，特定的成员展示了这些微生物的多样化能力： 门通过其嗜热和光合生长表现出适应性，而 纲的成员则以在复杂有机化合物的降解中发挥作用而闻名，它们在厌氧环境中的碳循环中做出了重大贡献，这突显了该门在不同环境条件下进行生物技术利用的潜力。在这方面， 门的代谢多样性必须被视为在广泛应用中具有巨大潜力的资产。目前，这个细菌门被组织成八个类群，每个类群都拥有不同的代谢策略，以在各种各样的极端环境中生存和繁衍。本综述将 门在这些环境中的生态作用与它们在生物技术方法中的代谢应用潜力联系起来。
