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生物医学研究文化：我们的所得与所想。

Research culture in biomedicine: what we learned, and what we would like to do about it.

机构信息

Department of Medicine, Harvard Medical School, Boston, MA, USA.

Blavatnik Institute of Cell Biology, Harvard Medical School, Boston, MA, USA.

出版信息

Commun Biol. 2024 May 7;7(1):546. doi: 10.1038/s42003-024-06237-y.

DOI:10.1038/s42003-024-06237-y
PMID:38714909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11076589/
Abstract

The significant stressors that affect the biomedical research community have the potential to negatively impact the conduct of science. Here we report on work done at Harvard Medical School to identify areas for improvement in research rigor, reproducibility, and responsibility in pursuit of continued research excellence.

摘要

影响生物医学研究界的重大压力因素有可能对科学研究产生负面影响。在此，我们报告了哈佛医学院所做的工作，以确定在追求卓越研究的过程中，在研究严谨性、可重复性和责任方面需要改进的领域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/452d/11076589/556af0f882a6/42003_2024_6237_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/452d/11076589/333f99687bd9/42003_2024_6237_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/452d/11076589/556af0f882a6/42003_2024_6237_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/452d/11076589/333f99687bd9/42003_2024_6237_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/452d/11076589/556af0f882a6/42003_2024_6237_Fig2_HTML.jpg

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本文引用的文献

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Prevalence of questionable research practices, research misconduct and their potential explanatory factors: A survey among academic researchers in The Netherlands.可疑研究行为、研究不端行为及其潜在解释因素的流行程度：荷兰学术研究人员的调查。
PLoS One. 2022 Feb 16;17(2):e0263023. doi: 10.1371/journal.pone.0263023. eCollection 2022.
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The Strategic Council for Research Excellence, Integrity, and Trust.卓越、诚信与信任研究战略委员会。
Proc Natl Acad Sci U S A. 2021 Oct 12;118(41). doi: 10.1073/pnas.2116647118.
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A community-led initiative for training in reproducible research.
一个社区主导的可重复性研究培训计划。
Elife. 2021 Jun 21;10:e64719. doi: 10.7554/eLife.64719.
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Postdocs under pressure: 'Can I even do this any more?'.博士后们压力重重：“我还能继续干这个吗？”
Nature. 2020 Nov;587(7835):689-692. doi: 10.1038/d41586-020-03235-y.
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The Hong Kong Principles for assessing researchers: Fostering research integrity.《评估研究人员的香港原则：促进研究诚信》
PLoS Biol. 2020 Jul 16;18(7):e3000737. doi: 10.1371/journal.pbio.3000737. eCollection 2020 Jul.
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Framework for advancing rigorous research.推进严谨研究的框架。
Elife. 2020 Mar 4;9:e55915. doi: 10.7554/eLife.55915.
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What Research Institutions Can Do to Foster Research Integrity.研究机构可以采取哪些措施来培养研究诚信
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Research Culture and Reproducibility.研究文化与可重复性。
Trends Cogn Sci. 2020 Feb;24(2):91-93. doi: 10.1016/j.tics.2019.12.002. Epub 2019 Dec 28.
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Implementation of a responsible conduct of research education program at Duke University School of Medicine.杜克大学医学院实施负责任研究行为教育计划。
Account Res. 2019 Jul;26(5):288-310. doi: 10.1080/08989621.2019.1621755. Epub 2019 Jun 2.