Department of Morphology, Genetics, Orthodontics and Pediatric Dentistry, School of Dentistry, São Paulo State University (Unesp), Araraquara, São Paulo, Brazil.
Department of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Orthod Craniofac Res. 2024 Oct;27(5):785-794. doi: 10.1111/ocr.12805. Epub 2024 May 7.
An ideal orthodontic treatment involves qualitative and quantitative measurements of dental and skeletal components to evaluate patients' discrepancies, such as facial, occlusal, and functional characteristics. Deciding between orthodontics and orthognathic surgery remains challenging, especially in borderline patients. Advances in technology are aiding clinical decisions in orthodontics. The increasing availability of data and the era of big data enable the use of artificial intelligence to guide clinicians' diagnoses. This study aims to test the capacity of different machine learning (ML) models to predict whether orthognathic surgery or orthodontics treatment is required, using soft and hard tissue cephalometric values.
A total of 920 lateral radiographs from patients previously treated with either conventional orthodontics or in combination with orthognathic surgery were used, comprising n = 558 Class II and n = 362 Class III patients, respectively. Thirty-two measures were obtained from each cephalogram at the initial appointment. The subjects were randomly divided into training (n = 552), validation (n = 183), and test (n = 185) datasets, both as an entire sample and divided into Class II and Class III sub-groups. The extracted data were evaluated using 10 machine learning models and by a four-expert panel consisting of orthodontists (n = 2) and surgeons (n = 2).
The combined prediction of 10 models showed top-ranked performance in the testing dataset for accuracy, F1-score, and AUC (entire sample: 0.707, 0.706, 0.791; Class II: 0.759, 0.758, 0.824; Class III: 0.822, 0.807, 0.89).
The proposed combined 10 ML approach model accurately predicted the need for orthognathic surgery, showing better performance in Class III patients.
理想的正畸治疗涉及到牙齿和骨骼成分的定性和定量测量,以评估患者的差异,如面部、咬合和功能特征。正畸治疗和正颌手术之间的选择仍然具有挑战性,尤其是在边缘患者中。技术的进步正在辅助正畸治疗的临床决策。越来越多的数据可用性和大数据时代使人工智能的使用能够指导临床医生的诊断。本研究旨在测试不同机器学习(ML)模型的能力,以使用软组织和硬组织头颅侧位片预测是否需要正颌手术或正畸治疗。
本研究共使用了 920 名接受过传统正畸治疗或与正颌手术联合治疗的患者的侧位头颅片,其中包括 n=558 名 Class II 患者和 n=362 名 Class III 患者。从每个头颅片的初始就诊时获得了 32 项测量值。受试者被随机分为训练(n=552)、验证(n=183)和测试(n=185)数据集,既作为一个整体样本,也分为 Class II 和 Class III 亚组。使用 10 种机器学习模型和由 2 名正畸医生和 2 名外科医生组成的 4 位专家小组对提取的数据进行评估。
在测试数据集的准确性、F1 评分和 AUC 中,10 个模型的综合预测表现最佳(整体样本:0.707、0.706、0.791;Class II:0.759、0.758、0.824;Class III:0.822、0.807、0.89)。
提出的联合 10 个 ML 方法模型准确地预测了正颌手术的需求,在 Class III 患者中表现出更好的性能。