School of Physical Therapy, Western University, London, Ontario, Canada.
Physiotherapy Department, London Health Science Center (LHSC), London, Ontario, Canada.
PLoS One. 2024 May 10;19(5):e0303365. doi: 10.1371/journal.pone.0303365. eCollection 2024.
INTRODUCTION/BACKGROUND: Neck pain is a burdensome condition associated with pain, disability, and economic cost. Neck pain has been associated with observable changes in neuromuscular function and biomechanics. Prior research shows impairments in kinematic control, including reduced mobility, velocity, and smoothness of cervical motion. However, the strength of association between these impairments and patient-reported pain and disability is unclear rendering development of novel and relevant rehabilitation strategies difficult. The aim of this systematic review is to synthesize existing evidence on the strength of association between clinical biomechanical metrics of neck function (ROM, strength, acceleration, accuracy, smoothness, etc.) and patient-reported neck pain and disability.
METHODS/ANALYSIS: This protocol follows Cochrane guidelines and adheres to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P). MEDLINE, EMBASE, CINAHL, SPORTDiscus, Web of Science and Scopus will be searched, along with the gray literature, up to 20 November 2023, using terms and keywords derived from initial scoping searches. Observational studies, including cohorts and cross-sectional studies, that explore associations between clinical biomechanics of the neck and patient-reported outcomes of neck pain or disability will be included. Two reviewers will independently perform study selection, data extraction, and risk of bias assessment (National Institute of Health tool). Data will be synthesized using either a random effects meta-analytic approach or qualitatively using a modified Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach, dependent on the homogeneity of data available.
This review addresses a gap in the literature by systematically synthesizing findings on the relationship between neck function impairments and patient-reported outcomes. It will identify priorities for neck pain rehabilitation and gaps in current knowledge.
The results of this review will be disseminated through a peer-reviewed publication, conference presentation, and lay language summaries posted on an open-access website.
PROSPERO Registration number: CRD42023417317. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023417317.
简介/背景：颈部疼痛是一种痛苦的疾病，与疼痛、残疾和经济成本有关。颈部疼痛与神经肌肉功能和生物力学的可观察变化有关。先前的研究表明，运动控制受损，包括颈椎运动的活动性、速度和流畅性降低。然而，这些损伤与患者报告的疼痛和残疾之间的关联强度尚不清楚，这使得新的和相关的康复策略的制定变得困难。本系统评价的目的是综合现有关于颈部功能（ROM、力量、加速度、准确性、流畅性等）的临床生物力学指标与患者报告的颈部疼痛和残疾之间关联强度的证据。
方法/分析：本方案遵循 Cochrane 指南，并遵守系统评价和荟萃分析报告的首选条目（PRISMA-P）。将对 MEDLINE、EMBASE、CINAHL、SPORTDiscus、Web of Science 和 Scopus 进行搜索，并结合灰色文献，直到 2023 年 11 月 20 日，使用从初始范围搜索中得出的术语和关键词。将纳入观察性研究，包括队列研究和横断面研究，这些研究探讨了颈部临床生物力学与颈部疼痛或残疾患者报告结果之间的关联。两名评审员将独立进行研究选择、数据提取和偏倚风险评估（国家卫生研究院工具）。将根据现有数据的同质性，使用随机效应荟萃分析方法或定性使用改良的推荐、评估、制定和评估（GRADE）方法对数据进行综合。
本综述通过系统地综合有关颈部功能障碍与患者报告结果之间关系的研究结果，解决了文献中的一个空白。它将确定颈部疼痛康复的优先事项和当前知识的差距。
本综述的结果将通过同行评议的出版物、会议演讲和张贴在开放获取网站上的通俗易懂的摘要进行传播。
PROSPERO 注册号：CRD42023417317。https://www.crd.york.ac.uk/prospero/display_record.php？ID=CRD42023417317。
