Raju Gagan, Ranjan Aashrayi, Banik Soumyabrata, Poddar Ashmini, Managuli Vishwanath, Mazumder Nirmal
Department of Biophysics, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka 576104 India.
Department of Mechanical and Industrial Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Karnataka 576104 India.
Biophys Rev. 2023 Dec 16;16(2):151-163. doi: 10.1007/s12551-023-01175-1. eCollection 2024 Apr.
Current-age smartphones are known for their wide array of functionality and are now being utilized in the field of healthcare and medicine due to their proven capabilities as smartphone imaging devices (SIDs). Recent technical advancements enabled the integration of special add-on lenses with smartphones to transform them into SIDs. With the rising demand for efficient point-of-care (PoC) devices for better diagnostic applications, SIDs will be a one-stop solution. Additionally, portability, user-friendliness and low-cost make it accessible for all even at remote locations. Furthermore, improvements in resolution, magnification and field-of-view (FOV) have attracted the scientific community to use SIDs in various biomedical applications such as disease diagnosis, food quality control and pathogen detection. SIDs can be arranged in various combinational setups by using different illumination sources and optics to achieve suitable contrast and visibility of the specimen under study. This Commentary illustrates the various illumination sources used in SID and also spotlights their design and applications.
当前时代的智能手机以其广泛的功能而闻名,由于其作为智能手机成像设备(SID)的可靠能力,现在正被应用于医疗保健和医学领域。最近的技术进步使得特殊附加镜头能够与智能手机集成,将其转变为SID。随着对用于更好诊断应用的高效即时检测(PoC)设备的需求不断增加,SID将成为一站式解决方案。此外,其便携性、用户友好性和低成本使得即使在偏远地区的所有人都能使用。此外,分辨率、放大倍率和视野(FOV)的提高吸引了科学界在各种生物医学应用中使用SID,如疾病诊断、食品质量控制和病原体检测。通过使用不同的照明源和光学器件,SID可以以各种组合设置进行排列,以实现所研究标本的合适对比度和可见性。本评论阐述了SID中使用的各种照明源,并突出了它们的设计和应用。