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中国针对轻度认知障碍老年人及其家庭照顾者的非药物干预实践的效果。

The Effects of a Nonpharmacological Intervention Practice for Older Adults with Mild Cognitive Impairment and Their Family Caregivers in China.

机构信息

Department of Social Sciences, Faculty of Social Science and Business Studies, University of Eastern Finland, Kuopio, Finland.

Department of Social Work, School of Social Development and Public Policy, Fudan University, Shanghai, China.

出版信息

J Gerontol Soc Work. 2024 Oct;67(7):1069-1088. doi: 10.1080/01634372.2024.2355152. Epub 2024 May 19.

Abstract

Mild cognitive impairment (MCI) marks a critical phase in the progression to dementia. In our study, social workers utilized the Multicomponent Nonpharmacological Intervention Approach (MCNIA) to aid MCI participants (N = 52) and their caregivers, dividing into intervention and control groups. The intervention group underwent an additional regimen of non-pharmacological therapies besides pharmacological treatment. Our findings highlighted that: 1) MCNIA significantly enhanced cognitive and daily living abilities in the intervention group; 2) Caregivers experienced reduced burdens and improved social support; 3) Correlation analyses involving biomarkers indicated that MCNIA was particularly effective in alleviating depression in those with slightly more severe cognitive impairment.

摘要

轻度认知障碍(MCI)标志着向痴呆症发展的关键阶段。在我们的研究中,社会工作者利用多组分非药物干预方法(MCNIA)来帮助 MCI 参与者(N=52)及其照顾者,将他们分为干预组和对照组。干预组在药物治疗的基础上还接受了额外的非药物治疗方案。我们的研究结果表明:1)MCNIA 显著提高了干预组的认知和日常生活能力;2)照顾者的负担减轻,社会支持改善;3)涉及生物标志物的相关分析表明,MCNIA 在缓解认知障碍稍严重的患者的抑郁方面特别有效。

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