Mileto Irene, Merla Cristina, Corbella Marta, Gaiarsa Stefano, Kuka Angela, Ghilotti Stefania, De Cata Pasquale, Baldanti Fausto, Cambieri Patrizia
Department of Microbiology & Virology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Specialization School of Microbiology and Virology, University of Pavia, 27100 Pavia, Italy.
Microorganisms. 2024 May 7;12(5):942. doi: 10.3390/microorganisms12050942.
is a facultative anaerobe Gram-positive bacillus, which is considered a zoonotic pathogen. causes erysipeloid, mainly in occupational groups such as veterinarians, slaughterhouse workers, farmers, and fishermen. Two cutaneous forms (localised and generalised) and a septicaemic form have been described. Here, we report the isolation of a strain of from a 56-year-old immunocompetent obese male admitted to Fondazione IRCCS Policlinico San Matteo Pavia (Italy). Blood cultures were collected and Gram-positive bacilli were observed. grew and was identified. Antimicrobial susceptibility tests were performed and interpreted with EUCAST breakpoints (PK-PD). The strain was susceptible to all the antibiotics tested, while it was intrinsically resistant to vancomycin. The clinical diagnosis of can be challenging, due to the broad spectrum of symptoms and potential side effects, including serious systemic infections such as heart diseases. In the case described, bacteraemia caused by was detected in a immunocompetent patient. Bacteraemia caused by is rare in immunocompetent people and blood cultures were proven to be essential for the diagnosis and underdiagnosis of this pathogen, which is possible due to its resemblance to other clinical manifestations.
是一种兼性厌氧革兰氏阳性杆菌，被认为是一种人畜共患病原体。主要引起类丹毒，多见于兽医、屠宰场工人、农民和渔民等职业群体。已描述了两种皮肤形式（局部和全身性）以及一种败血症形式。在此，我们报告从一名入住意大利帕维亚圣马泰奥综合医院基金会（Fondazione IRCCS Policlinico San Matteo Pavia）的56岁免疫功能正常的肥胖男性中分离出一株[细菌名称未给出]。采集了血培养物并观察到革兰氏阳性杆菌。[细菌名称未给出]生长并被鉴定。进行了抗菌药物敏感性试验，并根据欧盟CAST断点（PK-PD）进行解释。该菌株对所有测试抗生素敏感，而对万古霉素具有固有抗性。由于症状范围广泛以及潜在的副作用，包括严重的全身感染如心脏病，[细菌名称未给出]的临床诊断可能具有挑战性。在所描述的病例中，在一名免疫功能正常的患者中检测到由[细菌名称未给出]引起的菌血症。由[细菌名称未给出]引起的菌血症在免疫功能正常的人群中很少见，血培养被证明对于该病原体的诊断和漏诊至关重要，这是因为它与其他临床表现相似。
