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成人先天性心脏病患者延长心律失常筛查的价值

Value of Extended Arrhythmia Screening in Adult Congenital Heart Disease Patients.

作者信息

Koole Maarten Antonius, de Jong Sanne, Mulder Barbara J, Bouma Berto Jorrit, Schuuring Mark Johan

机构信息

Department of Cardiology, Amsterdam UMC Amsterdam, the Netherlands.

Cardiology Centres of the Netherlands Amsterdam, the Netherlands.

出版信息

Arrhythm Electrophysiol Rev. 2024 Apr 8;13:e07. doi: 10.15420/aer.2023.28. eCollection 2024.

Abstract

The European Society of Cardiology guidelines for the management of adult congenital heart disease patients recommend screening for arrhythmias and bradycardias in symptomatic patients, often being done by means of an ambulatory 24-48-hour Holter or implantable loop recorder (ILR). However, nowadays non-invasive instruments, such as patches, smartwatches and smartphones based on single-lead ECGs that perform extended monitoring, are also available. The aim of this narrative review was to assess whether these instruments, when they detect arrhythmias and bradycardias in patients with adult congenital heart disease, will lead to meaningful changes in clinical care. Clinically meaningful changes include adjustment of medication, cardioversion, electrophysiology study, ablation or implantation of a cardiovascular implantable electronic device. The following monitoring instruments are discussed: cumulative Holter, 2-week continuous monitor, smartwatchand smartphone-based single-lead ECG, and ILR. The diagnostic yield of extended rhythm monitoring is high, and varies between 18% (smartphone-based single-lead ECG) and 41% with ILR. In conclusion, contemporary arrhythmia screening includes various new non-invasive technologies that are promising new tools as an alternative to Holter monitoring or ILR. However, the optimal mode of detection is still unclear due to the lack of head-to-head comparisons.

摘要

欧洲心脏病学会关于成人先天性心脏病患者管理的指南建议,对有症状的患者进行心律失常和心动过缓筛查,通常通过24 - 48小时动态心电图监测或植入式循环记录仪(ILR)来完成。然而,如今基于单导联心电图进行长时间监测的无创仪器,如贴片、智能手表和智能手机也已问世。本叙述性综述的目的是评估这些仪器在检测成人先天性心脏病患者的心律失常和心动过缓时,是否会导致临床护理发生有意义的改变。临床上有意义的改变包括调整药物治疗、心脏复律、电生理检查、消融或植入心血管植入式电子设备。本文讨论了以下监测仪器:累积动态心电图监测、两周连续监测、基于智能手表和智能手机的单导联心电图监测以及植入式循环记录仪。长时间心律监测的诊断率很高,在基于智能手机的单导联心电图监测中为18%,在植入式循环记录仪监测中为41%。总之,当代心律失常筛查包括各种新的无创技术,这些技术有望成为替代动态心电图监测或植入式循环记录仪监测的新工具。然而,由于缺乏直接比较,最佳检测模式仍不明确。

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