UAA或UGA是核糖体起始识别信号的一部分吗？
Is UAA or UGA part of the recognition signal for ribosomal initiation?
作者信息
Atkins J F
出版信息
Nucleic Acids Res. 1979 Oct 25;7(4):1035-41. doi: 10.1093/nar/7.4.1035.
Abstract
In none of the 92 published prokaryotic sequences is a translation codon preceeded by UAG as the first "termination codon". In most cases the UAA or UGA is close to the initiation codon and may be part of the ribosome recognition signal.
摘要
在已发表的92个原核生物序列中，没有一个翻译密码子之前的第一个“终止密码子”是UAG。在大多数情况下，UAA或UGA靠近起始密码子，可能是核糖体识别信号的一部分。
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2
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Cold Spring Harb Symp Quant Biol. 1969;34:499-503. doi: 10.1101/sqb.1969.034.01.056.
3
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Cold Spring Harb Symp Quant Biol. 1969;34:479-88. doi: 10.1101/sqb.1969.034.01.054.
4
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