Papakonstantinou Eleni, Dragoumani Konstantina, Mataragka Antonia, Bacopoulou Flora, Yapijakis Christos, Balatsos Nikolaos Aa, Pissaridi Katerina, Ladikos Dimitris, Eftymiadou Aspasia, Katsaros George, Gikas Evangelos, Hatzis Pantelis, Samiotaki Martina, Aivaliotis Michalis, Megalooikonomou Vasileios, Giannakakis Antonis, Iliopoulos Costas, Bongcam-Rudloff Erik, Kossida Sofia, Eliopoulos Elias, Chrousos George P, Vlachakis Dimitrios
Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, Athens, Greece.
University Research Institute of Maternal and Child Health & Precision Medicine, and UNESCO Chair on Adolescent Health Care, National and Kapodistrian University of Athens, "Aghia Sophia" Children's Hospital, Athens, Greece.
EMBnet J. 2024;29. doi: 10.14806/ej.29.0.1048. Epub 2024 May 22.
Breast milk, often referred to as "liquid gold," is a complex biofluid that provides essential nutrients, immune factors, and developmental cues for newborns. Recent advancements in the field of exosome research have shed light on the critical role of exosomes in breast milk. Exosomes are nanosized vesicles that carry bioactive molecules, including proteins, lipids, nucleic acids, and miRNAs. These tiny messengers play a vital role in intercellular communication and are now being recognized as key players in infant health and development. This paper explores the emerging field of milk exosomics, emphasizing the potential of exosome fingerprinting to uncover valuable insights into the composition and function of breast milk. By deciphering the exosomal cargo, we can gain a deeper understanding of how breast milk influences neonatal health and may even pave the way for personalized nutrition strategies.
母乳,常被称为“液体黄金”,是一种复杂的生物流体,为新生儿提供必需的营养、免疫因子和发育线索。外泌体研究领域的最新进展揭示了外泌体在母乳中的关键作用。外泌体是携带生物活性分子(包括蛋白质、脂质、核酸和微小RNA)的纳米级囊泡。这些微小的信使在细胞间通讯中发挥着至关重要的作用,现在被认为是婴儿健康和发育的关键因素。本文探讨了乳汁外泌体组学这一新兴领域,强调了外泌体指纹识别在揭示母乳组成和功能方面有价值见解的潜力。通过解读外泌体所载物质,我们可以更深入地了解母乳如何影响新生儿健康,甚至可能为个性化营养策略铺平道路。