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曼彻斯特手术与骶棘韧带悬吊带术治疗子宫脱垂的结局比较:英国泌尿妇科协会数据库研究。

The Outcomes of the Manchester Procedure Versus Sacrospinous Ligament Hysteropexy for Uterine Prolapse: A Study of the British Society of Urogynaecology Database.

机构信息

Department of Urogynaecology, Birmingham Women's and Children NHS Foundation Trust, Birmingham, UK.

出版信息

Int Urogynecol J. 2024 Jul;35(7):1469-1475. doi: 10.1007/s00192-024-05826-z. Epub 2024 Jun 7.

Abstract

INTRODUCTION

The Manchester procedure (MP) and sacrospinous ligament hysteropexy (SSHP) have long been established as effective conservative surgeries for treating uterine prolapse. However, there have been limited studies on outcomes comparing these two techniques.

METHODOLOGY

This was a prospective cohort study of the British Society of Urogynaecology database between February 2007 and 2023 of MP and SSHP outcomes from 90 centres in the UK. The primary outcome was the Patient Global Impression of Improvement (PGI-I). The other outcomes compared were the absence of pelvic organ prolapse beyond the hymen in any compartment evaluated by the Pelvic Organ Prolapse Quantification (POP-Q), complications, and the incidence of reported symptomatic prolapse within 1 year after the operation.

RESULTS

There were 718 women who underwent MP and 2,384 who had SSHP. The PGI-I score was significantly better in the MP group (p value <0.001). The rates of symptomatic prolapse within 1 year (odds ratio [OR] 0.36, 95% confidence interval [CI] 0.18-0.69; p value 0.001), recurrence of prolapse beyond the hymen (OR 0.13, 95% CI 0.03-0.53; p value 0.001) and apical recurrence (OR 0.09, 95% CI 0.01-0.65; p value 0.003) during follow-up examination were lower in the MP group. The combined peri-operative and post-operative complications reported in both groups were comparatively similar.

CONCLUSION

The symptom improvement was better and recurrence was lower with the MP than with SSHP at short-term follow-up.

摘要

简介

曼彻斯特手术(MP)和骶骨固定术(SSHP)长期以来一直被认为是治疗子宫脱垂的有效保守手术。然而,关于这两种技术的比较结果的研究有限。

方法

这是一项对英国尿妇科协会数据库的前瞻性队列研究,该研究纳入了 2007 年 2 月至 2023 年期间英国 90 个中心的 MP 和 SSHP 治疗结果。主要结局是患者总体改善印象(PGI-I)。比较的其他结局包括盆腔器官脱垂定量(POP-Q)评估的任何部位处女膜外的盆腔器官脱垂不存在、并发症以及手术后 1 年内报告的有症状脱垂的发生率。

结果

共有 718 名女性接受了 MP,2384 名女性接受了 SSHP。MP 组的 PGI-I 评分显著更好(p 值<0.001)。1 年内有症状脱垂的发生率(比值比 [OR] 0.36,95%置信区间 [CI] 0.18-0.69;p 值<0.001)、处女膜外脱垂复发率(OR 0.13,95% CI 0.03-0.53;p 值<0.001)和随访检查中顶脱垂复发率(OR 0.09,95% CI 0.01-0.65;p 值<0.001)在 MP 组较低。两组报告的围手术期和术后并发症发生率相当。

结论

短期随访时,MP 比 SSHP 症状改善更好,复发率更低。

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