Pezzlo M T, Wetkowski M A, Peterson E M, de la Maza L M
J Clin Microbiol. 1985 Apr;21(4):578-81. doi: 10.1128/jcm.21.4.578-581.1985.
A study was performed to evaluate two rapid urine screening methods, Bac-T-Screen (Marion Laboratories, Inc., Kansas City, Mo.) and Chemstrip LN (Boehringer Mannheim Diagnostics, BioDynamics, Indianapolis, Ind.), for their ability to screen for bacteriuria and pyuria within 2 min. A total of 1,000 urine specimens were tested with the Bac-T-Screen and the Chemstrip LN and compared with a semiquantitative plate culture method. Of the 1,000 specimens tested, 249 had colony counts of greater than or equal to 10(5) CFU/ml by the culture method. Of these, the Bac-T-Screen detected 94.8% (236 of 249) and the Chemstrip LN detected 84.7% (210 of 249). There were 120 pure cultures of probable pathogens of which the Bac-T-Screen detected 97.5% (117 of 120) and the Chemstrip LN detected 91.7% (110 of 120). Leukocyte counts were performed on all specimens, and both methods have the ability to detect greater than 10 leukocytes per mm3 in a majority (greater than 93%) of the specimens. The cost per test for a negative screen is approximately $1.30 for the Bac-T-Screen and $0.40 for the Chemstrip LN. Overall there is a similar negative predictive value with both methods for bacteriuria and pyuria.
开展了一项研究，以评估两种快速尿液筛查方法——Bac-T-Screen（马里恩实验室公司，密苏里州堪萨斯城）和Chemstrip LN（勃林格曼海姆诊断公司，生物动力学部，印第安纳州印第安纳波利斯）在2分钟内筛查菌尿和脓尿的能力。总共1000份尿液标本用Bac-T-Screen和Chemstrip LN进行检测，并与半定量平板培养法进行比较。在检测的1000份标本中，通过培养法有249份菌落计数大于或等于10⁵CFU/ml。其中，Bac-T-Screen检测出94.8%（249份中的236份），Chemstrip LN检测出84.7%（249份中的210份）。有120份可能病原体的纯培养物，其中Bac-T-Screen检测出97.5%（120份中的117份），Chemstrip LN检测出91.7%（120份中的110份）。对所有标本进行了白细胞计数，两种方法都能够在大多数（大于93%）标本中检测到每立方毫米大于10个白细胞。Bac-T-Screen阴性筛查的每次检测成本约为1.30美元，Chemstrip LN为0.40美元。总体而言，两种方法对菌尿和脓尿的阴性预测值相似。
