Hopkins Steven, Gajagowni Saivaroon, Qadeer Yusuf, Wang Zhen, Virani Salim S, Meurman Jukka H, Leischik Roman, Lavie Carl J, Strauss Markus, Krittanawong Chayakrit
Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.
Am Heart J Plus. 2024 May 24;43:100407. doi: 10.1016/j.ahjo.2024.100407. eCollection 2024 Jul.
Epidemiological evidence has revealed a potential relationship between periodontal disease and cardiovascular disease (CVD). Consensus regarding a link between these pathologies remains elusive, however, largely secondary to the considerable overlap between risk factors and comorbidities common to both disease processes. This review article aims to update the evidence for an association by summarizing the evidence for causality between periodontitis and comorbidities linked to CVD, including endocarditis, hypertension (HTN), atrial fibrillation (AF), coronary artery disease (CAD), diabetes mellitus (DM) and hyperlipidemia (HLD). This article additionally discusses the role for periodontal therapy to improved management of the comorbidities, with the larger goal of examining the value of periodontal therapy on reduction of CVD risk. In doing so, we endeavor to further the understanding of the commonality between periodontitis, and CVD.
流行病学证据显示，牙周病与心血管疾病（CVD）之间存在潜在联系。然而，关于这些病理状况之间联系的共识仍然难以达成，这主要是因为两种疾病过程中常见的危险因素和合并症有相当大的重叠。这篇综述文章旨在通过总结牙周炎与与心血管疾病相关的合并症（包括心内膜炎、高血压（HTN）、心房颤动（AF）、冠状动脉疾病（CAD）、糖尿病（DM）和高脂血症（HLD））之间因果关系的证据，来更新两者关联的证据。本文还讨论了牙周治疗在改善合并症管理方面的作用，其更大的目标是研究牙周治疗对降低心血管疾病风险的价值。通过这样做，我们努力进一步理解牙周炎和心血管疾病之间的共性。
