Vaes Anouk W, Burtin Chris, Casaburi Richard, Celli Bartolome R, Evans Rachael A, Lareau Suzanne C, Nici Linda, Rochester Carolyn L, Troosters Thierry
Department of Research and Development, Ciro, Horn, The Netherlands.
REVAL - Rehabilitation Research Center, BIOMED - Biomedical Research Institute, Faculty of Rehabilitation Sciences, Hasselt University, Diepenbeek, Belgium.
Breathe (Sheff). 2024 Jun 11;20(2):230179. doi: 10.1183/20734735.0179-2023. eCollection 2024 Jun.
Exercise limitation and physical inactivity are separate, but related constructs. Both are commonly present in individuals with COPD, contribute to disease burden over and above the respiratory impairments, and are independently predictive of adverse outcomes. Because of this, clinicians should consider assessing these variables in their patients with COPD. Field tests of exercise performance such as the 6-min walk test and the incremental and endurance shuttle walk tests require limited additional resources, and results correlate with negative outcomes. Laboratory measures of exercise performance using a treadmill or cycle ergometer assess exercise capacity, provide prognostic information and have the advantage of explaining physiological mechanisms (and their interactions) underpinning exercise limitation. Limitations in exercise capacity ( "cannot do") and physical inactivity ( "do not do") are both associated with mortality; exercise limitation appears to be the more important driver of this outcome.
运动受限和身体不活动是两个不同但相关的概念。两者在慢性阻塞性肺疾病（COPD）患者中都很常见，除了呼吸功能损害外，还会加重疾病负担，并且都能独立预测不良后果。因此，临床医生应考虑对其COPD患者评估这些变量。运动表现的现场测试，如6分钟步行试验、递增式和耐力穿梭步行试验，所需的额外资源有限，且结果与不良后果相关。使用跑步机或自行车测力计进行的运动表现实验室测量可评估运动能力，提供预后信息，并且具有解释运动受限背后生理机制（及其相互作用）的优势。运动能力受限（“不能做”）和身体不活动（“不做”）均与死亡率相关；运动受限似乎是这一结果的更重要驱动因素。
