Grafl H J, Schwantes H O
Zentralbl Mikrobiol. 1985;140(1):3-11.
The in vivo influence of cadmium, zinc, lead, and mercury on the activities of intracellular enzymes in Saccharomyces cerevisiae has been studied. Cadmium and lead cause a significant increase of the enzyme activities. Zinc and mercury do not affect the enzyme activities but they intensify considerably the effects of cadmium and lead. A reduction of enzyme activities is found only rarely. Interactions between the heavy metals tested can lead to synergism or to antagonism or rather to an addition of the effects. The findings suggest that under in vivo conditions heavy metals show only an indirect influence on intracellular enzymes.
研究了镉、锌、铅和汞对酿酒酵母细胞内酶活性的体内影响。镉和铅会导致酶活性显著增加。锌和汞不影响酶活性，但它们会大大增强镉和铅的影响。仅偶尔发现酶活性降低。所测试的重金属之间的相互作用可导致协同作用、拮抗作用，或者更确切地说是作用的叠加。研究结果表明，在体内条件下，重金属对细胞内酶仅表现出间接影响。
