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通过病原体诊断和“同一健康”倡议探索疾病管理与控制:简要综述

Exploring Disease Management and Control through Pathogen Diagnostics and One Health Initiative: A Concise Review.

作者信息

Mukherjee Riya, Vidic Jasmina, Auger Sandrine, Wen Hsiao-Chuan, Pandey Ramendra Pati, Chang Chung-Ming

机构信息

Graduate Institute of Biomedical Sciences, Chang Gung University, Taoyuan 33302, Taiwan.

Master & Ph.D. Program in Biotechnology Industry, Chang Gung University, Taoyuan 33302, Taiwan.

出版信息

Antibiotics (Basel). 2023 Dec 23;13(1):17. doi: 10.3390/antibiotics13010017.

Abstract

The "One Health" initiative is a critical strategy that recognizes the interconnectedness between human, animal, and environmental health in the spread and containment of infectious pathogens. With the ease of global transportation, transboundary disease outbreaks pose a significant threat to food safety and security, endangering public health and having a negative economic impact. Traditional diagnostic techniques based on genotypic and phenotypic analyses are expensive, time-consuming, and cannot be translated into point-of-care tools, hindering effective disease management and control. However, with advancements in molecular methods, biosensors, and new generation sequencing, rapid and reliable diagnostics are now available. This review provides a comprehensive insight into emergent viral and bacterial pathogens and antimicrobial resistance, highlighting the importance of "One Health" in connecting detection and effective treatment. By emphasizing the symbiotic relationship between human and animal health, this paper underscores the critical role of "One Health" initiatives in preventing and controlling infectious diseases.

摘要

“同一健康”倡议是一项关键战略,它认识到在传染病原体的传播和控制方面,人类、动物和环境卫生之间存在着相互联系。随着全球运输的便捷,跨境疾病暴发对食品安全和保障构成重大威胁,危及公众健康并产生负面经济影响。基于基因型和表型分析的传统诊断技术成本高昂、耗时且无法转化为即时检测工具,阻碍了疾病的有效管理和控制。然而,随着分子方法、生物传感器和新一代测序技术的进步,现在已有快速且可靠的诊断方法。本综述全面深入地探讨了新出现的病毒和细菌病原体以及抗菌药物耐药性,强调了“同一健康”在连接检测与有效治疗方面的重要性。通过强调人类和动物健康之间的共生关系,本文突显了“同一健康”倡议在预防和控制传染病方面的关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e4c/10812768/c04066bd0303/antibiotics-13-00017-g001.jpg

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