Chair and Department of Oral Surgery, Medical University of Lublin, 20-093 Lublin, Poland.
Department of Experimental Immunology, Medical University of Lublin, 20-093 Lublin, Poland.
Int J Mol Sci. 2024 Jun 1;25(11):6115. doi: 10.3390/ijms25116115.
Periodontitis is a common oral condition that can have a significant impact on the overall health of the body. In recent years, attention has been paid to potential relationships between periodontitis and various hematological disorders. This publication aims to present information available in the literature on this relationship, focusing on examples of red blood cell disorders (such as aplastic anemia and sickle cell anemia) and white blood cell disorders (such as cyclic neutropenia, maladaptive trained immunity, clonal hematopoiesis, leukemia, and multiple myeloma). Understanding these associations can help physicians and dentists better diagnose, monitor, and treat patients associated with both groups of conditions, highlighting the need for interdisciplinary care for patients with oral disorders and hematologic diseases.
牙周炎是一种常见的口腔疾病，它会对全身健康产生重大影响。近年来，人们开始关注牙周炎与各种血液疾病之间的潜在关系。本出版物旨在介绍文献中有关这种关系的信息，重点介绍红细胞疾病（如再生障碍性贫血和镰状细胞贫血）和白细胞疾病（如周期性中性粒细胞减少症、适应性训练免疫、克隆性造血、白血病和多发性骨髓瘤）的例子。了解这些关联可以帮助医生和牙医更好地诊断、监测和治疗与这两组疾病相关的患者，突出了对口腔疾病和血液疾病患者进行跨学科治疗的必要性。
