Department of Food Science and Human Nutrition, College of Agriculture and Food, Qassim University, Buraydah 51452, Saudi Arabia.
Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah 51452, Saudi Arabia.
Nutrients. 2024 Jun 6;16(11):1794. doi: 10.3390/nu16111794.
Nutritional bars (NBs) are gaining popularity among healthy and athletic individuals, but postprandial antioxidative response has not been investigated. Therefore, the current study examined the postprandial alterations in total phenolic content (TPC), total antioxidant capacity (T-AOC), malondialdehyde (MDA), and Superoxide dismutase (SOD) in the plasma of healthy individuals after the ingestion of 140 g (510 Kcal) from formulated date-based bars (DBBs) or fruit-based bars (FBBs). Firstly, the free and bound phenolic contents (PCs) were determined to be 10.15 and 12.98 and 6.19 and 3.57 mg GAE g, respectively. FBBs were significantly higher in free PC than DBBs, while DBBs were considerably higher in bound PC than FBBs. Secondly, twenty participants with age, height, weight, body mass index (BMI), fat mass, and fat-free mass averages of 21.4 years, 170.0 cm, 66.3 kg, 22.9 kg m, 14.5, and 29.2 kg, respectively, were subjected to metabolic experiments (ISRCTN19386758). Ingestion of 140 g of FBB or DBB resulted in 288.50 or 302.14 µg TPC mL blood, respectively. Postprandial TPC content increased with time progression and peaked after 120 min. T-AOC contents averaged 22.63 and 23.61 U mL before ingestion of FBBs or DBBs, respectively. The T-AOC content increased significantly 120 and 180 min after ingestion of DBBs, while no significant change was noted after consuming FBBs. A significant decrease in MDA content was observed 180 min after consuming DBBs, while no significant change was noted after consuming FBBs. SOD concentrations ranged from 193.99 to 201.07 U L in FBBs and DBBs, respectively. No considerable response was noted up to 3 h after ingestion of FBBs. On the contrary, a significant response was found 120 min after consuming DBBs. Pearson's correlation coefficient indicated a highly significant positive correlation coefficient ( < 0.01) between T-AOC and either MDA or SOD, as well as between MDA and SOD. The principal component analysis demonstrated a strong and positive relationship between SOD and TPC at 60 and 120 min after DBB ingestion. In conclusion, the relative changes in postprandial responses in T-AOC and MDA did not significantly ( > 0.05) differ between DBBs and FBBs, except for TPC ( = 0.04, paired -test) and SOD ( = 0.003, paired -test). Further studies with an extended experimental time are needed to confirm the current findings.
营养棒（NBs）在健康和运动人群中越来越受欢迎，但尚未研究其餐后的抗氧化反应。因此，本研究检测了健康个体摄入 140 克（510 卡路里）配方日期棒（DBBs）或水果棒（FBBs）后血浆中总酚含量（TPC）、总抗氧化能力（T-AOC）、丙二醛（MDA）和超氧化物歧化酶（SOD）的餐后变化。首先，确定游离和结合酚含量（PCs）分别为 10.15 和 12.98 以及 6.19 和 3.57 mg GAE g。FBB 中的游离 PC 明显高于 DBB，而 DBB 中的结合 PC 明显高于 FBB。其次，20 名参与者的年龄、身高、体重、体重指数（BMI）、体脂肪和去脂体重平均值分别为 21.4 岁、170.0cm、66.3kg、22.9kg m、14.5kg 和 29.2kg，进行了代谢实验（ISRCTN19386758）。摄入 140 克 FBB 或 DBB 后，血液中的 TPC 含量分别为 288.50 或 302.14µg TPC mL。TPC 含量随时间的推移而增加，并在 120 分钟后达到峰值。T-AOC 含量在摄入 FBB 或 DBB 之前分别为 22.63 和 23.61 U mL。摄入 DBB 后 120 和 180 分钟 T-AOC 含量显著增加，而摄入 FBB 后无明显变化。摄入 DBB 后 180 分钟 MDA 含量明显下降，而摄入 FBB 后无明显变化。FBB 和 DBB 中的 SOD 浓度分别为 193.99 至 201.07 U L。摄入 FBB 后 3 小时内无明显反应。相反，摄入 DBB 后 120 分钟发现了显著反应。Pearson 相关系数表明，T-AOC 与 MDA 或 SOD 之间，以及 MDA 与 SOD 之间存在高度显著的正相关系数（<0.01）。主成分分析表明，DBB 摄入后 60 和 120 分钟时 SOD 与 TPC 之间存在强烈而积极的关系。总之，除 TPC（=0.04，配对检验）和 SOD（=0.003，配对检验）外，DBB 和 FBB 之间餐后 T-AOC 和 MDA 的相对变化无显著差异（>0.05）。需要进一步延长实验时间的研究来证实目前的发现。
Zotero 插件
