College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China.
Molecules. 2024 May 21;29(11):2415. doi: 10.3390/molecules29112415.
Myocardial infarction (MI) is one of the most prevalent types of cardiovascular disease. During MI, myocardial cells become ischemic and necrotic due to inadequate blood perfusion, leading to irreversible damage to the heart. Despite the development of therapeutic strategies for the prevention and treatment of MI, their effects are still unsatisfactory. Nanoparticles represent a new strategy for the pre-treatment and treatment of MI, and novel multifunctional nanoparticles with preventive and therapeutic capabilities hold promise for the prevention and treatment of this disease. This review summarizes the common types and properties of nanoparticles, and focuses on the research progress of nanoparticles for the prevention and treatment of MI.
心肌梗死（MI）是最常见的心血管疾病类型之一。在 MI 中，由于血液灌注不足，心肌细胞发生缺血和坏死，导致心脏不可逆转的损伤。尽管已经开发出用于 MI 的预防和治疗的治疗策略，但它们的效果仍然不尽人意。纳米颗粒代表了 MI 的预处理和治疗的新策略，具有预防和治疗功能的新型多功能纳米颗粒有望预防和治疗这种疾病。本综述总结了纳米颗粒的常见类型和特性，并重点介绍了用于 MI 的预防和治疗的纳米颗粒的研究进展。
