Guedea Marc, Sánchez Meritxell, Lozano Alicia, Ferrer Montse, Pont Angels, Guedea Ferran, Clotet Sandra, Juárez Marc, Araguas Pablo, Ventura Montse, d'Oliveira Nuno Gustavo, Ustrell Josep Maria
Orthodontics Department, Facultat de Medicina i Ciències de la Salut, University of Barcelona (UB), Barcelona, Spain.
Radiation Oncology Department, Institut Català d'Oncologia (ICO), Hospital Duran I Reynals, L'Hospitalet de Llobregat, Barcelona, Spain.
Clin Transl Oncol. 2025 Jan;27(1):166-174. doi: 10.1007/s12094-024-03567-5. Epub 2024 Jun 23.
This study aimed to examine health-related quality of life (HRQoL) in head and neck cancer patients at 1 and 5 years after successful treatment of their tumors, and to explore the usefulness of 2 instruments for assessing the need of dental care services.
This cross-sectional pilot study included 20 adult patients with head and neck cancer who completed the Functional Assessment of Cancer Therapy-Head and Neck (FACT H&N) Symptom Index and the European Organization for Research and Treatment of Cancer Quality of Life Head and Neck Module (EORTC QLQ-H&N43) after 1 and 5 years of treatment.
Mean (standard deviation, SD) scores of the FACT H&N Symptom Index were higher (better HRQoL) at 5 years than at 1 year (24.1 [4.4] vs. 21.1 [6.4]; p = 0.236). Only three of the ten items of FACT H&N (swallow, pain in mouth/throat or neck, and solid foods) evaluated oral health. In the EORTC QLQ-H&N43 questionnaire, scores were lower at 5 years (better HRQoL) in almost all multi- and single-item symptoms. This questionnaire includes four multi-item scales (pain in the mouth, social eating, swallowing, and problems with teeth) measuring dental and orthodontic needs.
HRQoL in patients with head and neck cancer improved with the length of follow-up. The EORTC QLQ-H&N43 has more items addressing oral health compared to the FACT H&N Symptom Index and may be more adequate to assess the need of dental therapy in clinical practice.
本研究旨在调查头颈部癌症患者肿瘤成功治疗后1年和5年的健康相关生活质量（HRQoL），并探讨两种评估牙科护理服务需求工具的实用性。
这项横断面试点研究纳入了20名成年头颈部癌症患者，他们在治疗1年和5年后完成了癌症治疗功能评估-头颈部（FACT H&N）症状指数和欧洲癌症研究与治疗组织生活质量头颈部模块（EORTC QLQ-H&N43）。
FACT H&N症状指数的平均（标准差，SD）得分在5年时高于1年（更好的HRQoL）（24.1[4.4]对21.1[6.4]；p=0.236）。FACT H&N的十个项目中只有三个（吞咽、口腔/喉咙或颈部疼痛以及固体食物）评估了口腔健康。在EORTC QLQ-H&N43问卷中，几乎所有多项目和单项目症状的得分在5年时都较低（更好的HRQoL）。该问卷包括四个多项目量表（口腔疼痛、社交进食、吞咽和牙齿问题），用于测量牙科和正畸需求。
头颈部癌症患者的HRQoL随着随访时间的延长而改善。与FACT H&N症状指数相比，EORTC QLQ-H&N43有更多涉及口腔健康的项目，可能更适合在临床实践中评估牙科治疗的需求。
