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大麻二酚在银屑病治疗中的前景。

The Perspective of Cannabidiol in Psoriasis Therapy.

作者信息

Stanescu Ana Maria Alexandra, Bejan Gabriel Cristian, Balta Mihaela Daniela, Andronic Octavian, Toma Cristian, Busnatu Stefan

机构信息

Department 5, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

Academy of Romanian Scientists (AOSR), Bucharest, Romania.

出版信息

Psoriasis (Auckl). 2024 Jun 19;14:51-61. doi: 10.2147/PTT.S469698. eCollection 2024.

Abstract

Psoriasis is a chronic skin condition that can significantly impact the quality of life of those affected. As an autoimmune disease, it can lead to itchy, painful, and scaly patches on the skin. Although various treatments, including topical creams, phototherapy, and systemic medications, are currently available, they may not always offer effective relief and can have side effects. Researchers have thus been exploring the potential benefits of non-psychoactive compounds such as CBD, found in Cannabis sativa plants, for treating psoriasis. CBD treatment may reduce inflammation, oxidative stress, itching, abnormal proliferation of keratinocytes, and may increase hydration. This review aims to provide an overview of the existing literature on the potential uses of CBD for psoriasis treatment.

摘要

银屑病是一种慢性皮肤病,会严重影响患者的生活质量。作为一种自身免疫性疾病,它会导致皮肤上出现瘙痒、疼痛和鳞屑斑块。尽管目前有多种治疗方法,包括外用乳膏、光疗和全身用药,但它们并不总是能有效缓解症状,还可能有副作用。因此,研究人员一直在探索大麻植物中发现的非精神活性化合物(如CBD)治疗银屑病的潜在益处。CBD治疗可能会减轻炎症、氧化应激、瘙痒,减少角质形成细胞的异常增殖,并可能增加皮肤水分。本综述旨在概述关于CBD治疗银屑病潜在用途的现有文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b211/11193997/128db89d2dde/PTT-14-51-g0001.jpg

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