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髋臼周围截骨术后的疼痛管理:系统评价。

Pain Management for Periacetabular Osteotomy: A Systematic Review.

机构信息

Department of Orthopedic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.

Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

出版信息

Iowa Orthop J. 2024;44(1):125-132.

Abstract

BACKGROUND

Early post-operative pain control is essential to facilitate rapid recovery after orthopaedic surgery. Despite periacetabular osteotomy (PAO) being the gold standard treatment of prearthritic hip dysplasia, there is limited evidence assessing efficacy of early post-operative pain management strategies. Recent literature has focused on non-opioid supplemental treatments such as nerve blocks or local wound infiltration. The purpose of this systematic review was to assess efficacy of these interventions to reduce pain, facilitate mobilization, reduce length of stay after PAO surgery.

METHODS

A systematic review was created under the guidance of PRISMA from databases that included PubMed, OVID Medline, Embase, SCOPUS, Cochrane Central Register of Clinical Trials, and clinicaltrials.gov from their creation dates to 12/21/23. These studies were screen based on predetermined inclusion and exclusion criteria.

RESULTS

A total of six studies were included in this analysis from independent institutions. Three investigated nerve blocks (fascia iliaca, pericapsular, transversus abdominis), one investigated local wound infiltration with ropivacaine, one investigated high-dose dexamethasone, and the last investigated removal of the epidural catheter on postoperative (POD) 1 compared to POD 2. There were heterogeneous outcomes that were measured from these studies. In general, nerve blocks decreased opioid use, pain, and length of hospital stay. The local wound infiltration decreased pain on POD 3 and 4. Removing the epidural catheter on POD1 compared to POD 2 decreased pain and length of stay. High-dose dexamethasone use decreased opioid use on POD 1, otherwise, there was no difference in pain.

CONCLUSION

In summary, supplemental pain management strategies peri-operatively for PAO surgery can decrease pain, opioid use, and length of hospital stay, though there are few studies assessing these interventions. Limiting opioid use after surgery reduces known negative consequences of the medication and facilitates rapid recovery. Clinical trials are needed that assess efficacy of supplemental pain management strategies after PAO surgery. .

摘要

背景

骨科手术后早期疼痛控制对于促进快速康复至关重要。尽管髋臼周围截骨术(PAO)是治疗髋关节发育不良的金标准,但目前评估早期术后疼痛管理策略效果的证据有限。最近的文献主要集中在非阿片类补充治疗上,如神经阻滞或局部伤口浸润。本系统评价的目的是评估这些干预措施减轻疼痛、促进活动、减少 PAO 手术后住院时间的效果。

方法

在 PRISMA 指导下,从包括 PubMed、OVID Medline、Embase、SCOPUS、Cochrane 临床试验中心注册库和 clinicaltrials.gov 在内的数据库中创建了一个系统评价,这些数据库的创建日期为 2023 年 12 月 21 日。这些研究是根据预先确定的纳入和排除标准进行筛选的。

结果

共有来自不同机构的 6 项研究纳入本分析。其中 3 项研究调查了神经阻滞(髂筋膜、囊周、腹横肌),1 项研究调查了局部伤口浸润罗哌卡因,1 项研究调查了高剂量地塞米松,最后 1 项研究调查了与术后第 2 天(POD2)相比,第 1 天(POD1)拔除硬膜外导管。这些研究的测量结果存在异质性。一般来说,神经阻滞可减少阿片类药物的使用、疼痛和住院时间。局部伤口浸润可减少 POD3 和 POD4 的疼痛。与 POD2 相比,POD1 拔除硬膜外导管可减少疼痛和住院时间。高剂量地塞米松使用可减少 POD1 时的阿片类药物使用,但疼痛无差异。

结论

总之,PAO 手术围手术期补充疼痛管理策略可减轻疼痛、减少阿片类药物使用和住院时间,但评估这些干预措施的研究较少。限制术后阿片类药物的使用可减少药物的已知不良后果,并促进快速康复。需要进行临床试验来评估 PAO 手术后补充疼痛管理策略的效果。

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